Automatic thyroid volume estimation in Graves' disease using planar scintigraphy

  • Jia Yann Huang*
  • , Ming Fong Tsai
  • , Kun Ju Lin
  • , Yung Sheng Chen
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Individualized dosage models are usually applied for radioiodine therapy in patients with Graves' hyperthyroidism. In these dosage plans, the thyroid volume is an important parameter. Thyroid volume determinations are usually obtained with ultrasonography or with scintigraphy. In this study, we proposed a novel thyroid volume estimation method using thyroid planar scintigraphy. An automatic thyroid volume calculation program based on image contrast enhancement and adaptive segmenation was developed. To validate the program, the results of automatic thyroid volume measurement from 34 patients were correlated with the results of ultrasonography. Our approach correlated well with ultrasonography (R2=0.97). From the satisfied result of this approach, we expect that this automatic computer-aided approach may be applied to help physicians in determination of the 131I therapy dosage to patients with Graves' disease.

Original languageEnglish
Title of host publicationProceedings of the 2009 2nd International Conference on Biomedical Engineering and Informatics, BMEI 2009
DOIs
StatePublished - 2009
Externally publishedYes
Event2009 2nd International Conference on Biomedical Engineering and Informatics, BMEI 2009 - Tianjin, China
Duration: 17 10 200919 10 2009

Publication series

NameProceedings of the 2009 2nd International Conference on Biomedical Engineering and Informatics, BMEI 2009

Conference

Conference2009 2nd International Conference on Biomedical Engineering and Informatics, BMEI 2009
Country/TerritoryChina
CityTianjin
Period17/10/0919/10/09

Keywords

  • Graves' disease
  • Image processing
  • Thyroid volume

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