Biological mechanism of shockwave in bone

Jai Hong Cheng, Ching Jen Wang*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

75 Scopus citations


Shockwave is a rapid, short duration acoustic wave that carries energy and can propagate through tissue medium. This kind of physical force can be a mechanical stimulus that induces biological effects in living tissue. Extracorporeal shockwave therapy (ESWT) acts as a mechanical stimulus which promotes biological healing processes through a mechanotransduction. The biological effects of ESWT are reported such as tissue regeneration, wound healing, angiogenesis, bone remodeling, and anti-inflammation. Until now, however, little is known about the basic mechanism of action of this type of therapy. This article describes the molecular mechanism on the current status of ESWT with pre-clinical and clinical applications for treating disorders in bone.

Original languageEnglish
Pages (from-to)143-146
Number of pages4
JournalInternational Journal of Surgery
StatePublished - 01 12 2015

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© 2015 IJS Publishing Group Limited.


  • Biological mechanism
  • Bone
  • Shockwave


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