Biosensor arrays based on surface plasmon resonance phase imaging

C. L. Wong, H. P. Ho, Y. K. Suen, Winnie W.Y. Chow, S. Y. Wu, W. J. Li, S. K. Kong, Chinlon Lin

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Scopus citations

Abstract

In this paper we present a biosensor design based on phase imaging of surface plasmon resonance (SPR). The system is adapted from our previously reported differential phase measurement scheme. We first conducted experiments on measuring the concentration of salt concentration in water in order to demonstrate the operation of this system. Biosensing experiments were performed to monitor the H3 influenza antigen-antibody binding interaction. In recent years, the needs for high-throughput biosensors in life sciences and biomedical areas have been increasing rapidly. Our phase-imaging SPR sensor is a non-labeling, real-time quantitative sensing approach compatible with the micro-array chip platform. It should therefore have a promising potential for various bio-related detection applications, such as clinical diagnostics.

Original languageEnglish
Title of host publicationProceedings of International Symposium on Biophotonics, Nanophotonics and Metamaterials, Metamaterials 2006
PublisherIEEE Computer Society
Pages95-98
Number of pages4
ISBN (Print)0780397746, 9780780397743
DOIs
StatePublished - 2006
Externally publishedYes
EventInternational Symposium on Biophotonics, Nanophotonics and Metamaterials, Metamaterials 2006 - Hangzhou, China
Duration: 16 10 200618 10 2006

Publication series

NameProceedings of International Symposium on Biophotonics, Nanophotonics and Metamaterials, Metamaterials 2006

Conference

ConferenceInternational Symposium on Biophotonics, Nanophotonics and Metamaterials, Metamaterials 2006
Country/TerritoryChina
CityHangzhou
Period16/10/0618/10/06

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