Biosensor based on degree of coherence of a pair of surface plasma waves

Chien Chou*, Chien Wa Ho, Sheng Yi Chang, Nai Chuan Chen, Ying Feng Chang, Li Chen Su, Cheng Chung Lee

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

1 Scopus citations

Abstract

A novel "degree of coherence paired surface plasma wave biosensor" (DOC-PSPWB) is proposed wherein the principle of detection involves the degree of coherence of highly correlated surface plasma waves when these are excited on a metal/dielectric interface within the DOC-PSPWB. Using the sensor, the concentration of total PSA (t-PSA) in a phosphate-buffered saline solution was measured, and a detection limit of 0.015pg/mL was determined experimentally. Finally, the dynamic range of the DOC-PSPWB when used on samples with ultralow molecular concentrations is discussed.

Original languageEnglish
Pages (from-to)25022-25027
Number of pages6
JournalJournal of Physical Chemistry C
Volume116
Issue number47
DOIs
StatePublished - 29 11 2012

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