Body mass index above 24 is beneficial for the 6-month survival rate in hepatocellular carcinoma patients with extrahepatic metastasess

Yueh Shih Chang; Jen Seng Huang; Cho Li Yen; Rong Nan Chien; Cheng Hsu Wang; Chien Hong Lai; Tsung Han Wu; Yii Jeng Lan; Kun Yun Yeh

doi:10.6133/apjcn.062016.03

Body mass index above 24 is beneficial for the 6-month survival rate in hepatocellular carcinoma patients with extrahepatic metastasess

Yueh Shih Chang, Jen Seng Huang, Cho Li Yen, Rong Nan Chien, Cheng Hsu Wang, Chien Hong Lai, Tsung Han Wu, Yii Jeng Lan, Kun Yun Yeh^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

3 Scopus citations

Abstract

Background and Objectives: To investigate the effect of overweight status on the 6-month survival rate in patients with extrahepatic hepatocellular carcinoma (HCC). Methods and Study Design: We retrospectively analyzed the records of 51 patients with hepatocellular carcinoma and extrahepatic metastases between 2007 and 2010 before treatment. The associations among overweight status (body mass index [BMI] > 24 kg/m²), demographic variables, and survival outcome were analyzed by univariate and multivariate analysis. Results: BMI > 24 kg/m² was significantly associated with the 6-month survival rate (p=0.042). Gender (p=0.149), Child Pugh classification (p=0.149), Okuda staging (p=0.093), and albumin concentration > 3.5 mg/dL (p=0.082) showed marginal survival benefits in univariate analysis. Multivariate analysis confirmed that BMI > 24 kg/m² was an independent prognostic factor for the 6-month survival rate (p=0.03). Conclusions: BMI > 24 kg/m² was associated with an improved 6-month survival rate in patients with extrahepatic metastatic hepatocellular carcinoma.

Original language	English
Pages (from-to)	637-641
Number of pages	5
Journal	Asia Pacific Journal of Clinical Nutrition
Volume	26
Issue number	4
DOIs	https://doi.org/10.6133/apjcn.062016.03
State	Published - 01 06 2017

Keywords

6-month survival
Body mass index
Extrahepatic
Hepatocellular carcinoma
Metastasis

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@article{bc8d0652795e48ae98aa24b780dddaf0,

title = "Body mass index above 24 is beneficial for the 6-month survival rate in hepatocellular carcinoma patients with extrahepatic metastasess",

abstract = "Background and Objectives: To investigate the effect of overweight status on the 6-month survival rate in patients with extrahepatic hepatocellular carcinoma (HCC). Methods and Study Design: We retrospectively analyzed the records of 51 patients with hepatocellular carcinoma and extrahepatic metastases between 2007 and 2010 before treatment. The associations among overweight status (body mass index [BMI] > 24 kg/m2), demographic variables, and survival outcome were analyzed by univariate and multivariate analysis. Results: BMI > 24 kg/m2 was significantly associated with the 6-month survival rate (p=0.042). Gender (p=0.149), Child Pugh classification (p=0.149), Okuda staging (p=0.093), and albumin concentration > 3.5 mg/dL (p=0.082) showed marginal survival benefits in univariate analysis. Multivariate analysis confirmed that BMI > 24 kg/m2 was an independent prognostic factor for the 6-month survival rate (p=0.03). Conclusions: BMI > 24 kg/m2 was associated with an improved 6-month survival rate in patients with extrahepatic metastatic hepatocellular carcinoma.",

keywords = "6-month survival, Body mass index, Extrahepatic, Hepatocellular carcinoma, Metastasis",

author = "Chang, {Yueh Shih} and Huang, {Jen Seng} and Yen, {Cho Li} and Chien, {Rong Nan} and Wang, {Cheng Hsu} and Lai, {Chien Hong} and Wu, {Tsung Han} and Lan, {Yii Jeng} and Yeh, {Kun Yun}",

year = "2017",

month = jun,

day = "1",

doi = "10.6133/apjcn.062016.03",

language = "英语",

volume = "26",

pages = "637--641",

journal = "Asia Pacific Journal of Clinical Nutrition",

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publisher = "HEC Press",

number = "4",

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TY - JOUR

T1 - Body mass index above 24 is beneficial for the 6-month survival rate in hepatocellular carcinoma patients with extrahepatic metastasess

AU - Chang, Yueh Shih

AU - Huang, Jen Seng

AU - Yen, Cho Li

AU - Chien, Rong Nan

AU - Wang, Cheng Hsu

AU - Lai, Chien Hong

AU - Wu, Tsung Han

AU - Lan, Yii Jeng

AU - Yeh, Kun Yun

PY - 2017/6/1

Y1 - 2017/6/1

N2 - Background and Objectives: To investigate the effect of overweight status on the 6-month survival rate in patients with extrahepatic hepatocellular carcinoma (HCC). Methods and Study Design: We retrospectively analyzed the records of 51 patients with hepatocellular carcinoma and extrahepatic metastases between 2007 and 2010 before treatment. The associations among overweight status (body mass index [BMI] > 24 kg/m2), demographic variables, and survival outcome were analyzed by univariate and multivariate analysis. Results: BMI > 24 kg/m2 was significantly associated with the 6-month survival rate (p=0.042). Gender (p=0.149), Child Pugh classification (p=0.149), Okuda staging (p=0.093), and albumin concentration > 3.5 mg/dL (p=0.082) showed marginal survival benefits in univariate analysis. Multivariate analysis confirmed that BMI > 24 kg/m2 was an independent prognostic factor for the 6-month survival rate (p=0.03). Conclusions: BMI > 24 kg/m2 was associated with an improved 6-month survival rate in patients with extrahepatic metastatic hepatocellular carcinoma.

AB - Background and Objectives: To investigate the effect of overweight status on the 6-month survival rate in patients with extrahepatic hepatocellular carcinoma (HCC). Methods and Study Design: We retrospectively analyzed the records of 51 patients with hepatocellular carcinoma and extrahepatic metastases between 2007 and 2010 before treatment. The associations among overweight status (body mass index [BMI] > 24 kg/m2), demographic variables, and survival outcome were analyzed by univariate and multivariate analysis. Results: BMI > 24 kg/m2 was significantly associated with the 6-month survival rate (p=0.042). Gender (p=0.149), Child Pugh classification (p=0.149), Okuda staging (p=0.093), and albumin concentration > 3.5 mg/dL (p=0.082) showed marginal survival benefits in univariate analysis. Multivariate analysis confirmed that BMI > 24 kg/m2 was an independent prognostic factor for the 6-month survival rate (p=0.03). Conclusions: BMI > 24 kg/m2 was associated with an improved 6-month survival rate in patients with extrahepatic metastatic hepatocellular carcinoma.

KW - 6-month survival

KW - Body mass index

KW - Extrahepatic

KW - Hepatocellular carcinoma

KW - Metastasis

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DO - 10.6133/apjcn.062016.03

M3 - 文章

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AN - SCOPUS:85020260819

SN - 0964-7058

VL - 26

SP - 637

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JO - Asia Pacific Journal of Clinical Nutrition

JF - Asia Pacific Journal of Clinical Nutrition

IS - 4

ER -

Body mass index above 24 is beneficial for the 6-month survival rate in hepatocellular carcinoma patients with extrahepatic metastasess

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