Briaexcavatins G and H, two new briaranes from the octocoral Briareum excavatum

Yu Pei Chen; Shwu Li Wu; Jui Hsin Su; Mei Ru Lin; Wan Ping Hu; Tsong Long Hwang; Jyh Horng Sheu; Tung Yung Fan; Lee Shing Fang; Ping Jyun Sung

doi:10.1246/bcsj.79.1900

Briaexcavatins G and H, two new briaranes from the octocoral Briareum excavatum

Yu Pei Chen, Shwu Li Wu, Jui Hsin Su, Mei Ru Lin, Wan Ping Hu, Tsong Long Hwang, Jyh Horng Sheu, Tung Yung Fan, Lee Shing Fang, Ping Jyun Sung^*

^*Corresponding author for this work

School of Traditional Chinese Medicine

Research output: Contribution to journal › Journal Article › peer-review

24 Scopus citations

Abstract

Two new briarane-related diterpenoids, designated as briaexcavatins G (1) and H (2), were isolated from the octocoral Briareum excavatum, collected off southern Taiwan coast. The structures, including the absolute stereochemistry of these two new metabolites, were established by spectroscopy and chemical conversion. The configuration of briarane 2 was further supported by molecular mechanics calculations. Briarane 1 showed weak inhibitory effects on human neutrophil elastase release.

Original language	English
Pages (from-to)	1900-1905
Number of pages	6
Journal	Bulletin of the Chemical Society of Japan
Volume	79
Issue number	12
DOIs	https://doi.org/10.1246/bcsj.79.1900
State	Published - 2006

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title = "Briaexcavatins G and H, two new briaranes from the octocoral Briareum excavatum",

abstract = "Two new briarane-related diterpenoids, designated as briaexcavatins G (1) and H (2), were isolated from the octocoral Briareum excavatum, collected off southern Taiwan coast. The structures, including the absolute stereochemistry of these two new metabolites, were established by spectroscopy and chemical conversion. The configuration of briarane 2 was further supported by molecular mechanics calculations. Briarane 1 showed weak inhibitory effects on human neutrophil elastase release.",

author = "Chen, {Yu Pei} and Wu, {Shwu Li} and Su, {Jui Hsin} and Lin, {Mei Ru} and Hu, {Wan Ping} and Hwang, {Tsong Long} and Sheu, {Jyh Horng} and Fan, {Tung Yung} and Fang, {Lee Shing} and Sung, {Ping Jyun}",

year = "2006",

doi = "10.1246/bcsj.79.1900",

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AU - Chen, Yu Pei

AU - Wu, Shwu Li

AU - Su, Jui Hsin

AU - Lin, Mei Ru

AU - Hu, Wan Ping

AU - Hwang, Tsong Long

AU - Sheu, Jyh Horng

AU - Fan, Tung Yung

AU - Fang, Lee Shing

AU - Sung, Ping Jyun

PY - 2006

Y1 - 2006

N2 - Two new briarane-related diterpenoids, designated as briaexcavatins G (1) and H (2), were isolated from the octocoral Briareum excavatum, collected off southern Taiwan coast. The structures, including the absolute stereochemistry of these two new metabolites, were established by spectroscopy and chemical conversion. The configuration of briarane 2 was further supported by molecular mechanics calculations. Briarane 1 showed weak inhibitory effects on human neutrophil elastase release.

AB - Two new briarane-related diterpenoids, designated as briaexcavatins G (1) and H (2), were isolated from the octocoral Briareum excavatum, collected off southern Taiwan coast. The structures, including the absolute stereochemistry of these two new metabolites, were established by spectroscopy and chemical conversion. The configuration of briarane 2 was further supported by molecular mechanics calculations. Briarane 1 showed weak inhibitory effects on human neutrophil elastase release.

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U2 - 10.1246/bcsj.79.1900

DO - 10.1246/bcsj.79.1900

M3 - 文章

AN - SCOPUS:33845586073

SN - 0009-2673

VL - 79

SP - 1900

EP - 1905

JO - Bulletin of the Chemical Society of Japan

JF - Bulletin of the Chemical Society of Japan

IS - 12

ER -

Briaexcavatins G and H, two new briaranes from the octocoral Briareum excavatum

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