Briaexcavatins G and H, two new briaranes from the octocoral Briareum excavatum

Yu Pei Chen, Shwu Li Wu, Jui Hsin Su, Mei Ru Lin, Wan Ping Hu, Tsong Long Hwang, Jyh Horng Sheu, Tung Yung Fan, Lee Shing Fang, Ping Jyun Sung*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

23 Scopus citations

Abstract

Two new briarane-related diterpenoids, designated as briaexcavatins G (1) and H (2), were isolated from the octocoral Briareum excavatum, collected off southern Taiwan coast. The structures, including the absolute stereochemistry of these two new metabolites, were established by spectroscopy and chemical conversion. The configuration of briarane 2 was further supported by molecular mechanics calculations. Briarane 1 showed weak inhibitory effects on human neutrophil elastase release.

Original languageEnglish
Pages (from-to)1900-1905
Number of pages6
JournalBulletin of the Chemical Society of Japan
Volume79
Issue number12
DOIs
StatePublished - 2006

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