Briarenolides H and I: New 8-hydroxybriarane diterpenoids from a Formosan octocoral Briareum sp. (Briareidae)

Yin Di Su*, Tsong Long Hwang, Nai Cheng Lin, Yung Husan Chen, Yang Chang Wu, Jyh Horng Sheu, Ping Jyun Sung

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

5 Scopus citations

Abstract

Chemical investigation on a Formosan octocoral identified as Briareum sp. has led to the isolation of two new 8-hydroxybriarane diterpenoids, briarenolides H (1) and I (2). The structures of briaranes 1 and 2 were established by spectroscopic methods and by comparison of the spectroscopic data with those of known briarane analogues. Briarenolide H (1) was proven to be the first 6-methoxybriarane derivative. Briarenolide I (2) displayed an inhibitory effect on the generation of superoxide anion by human neutrophils.

Original languageEnglish
Pages (from-to)1031-1036
Number of pages6
JournalBulletin of the Chemical Society of Japan
Volume85
Issue number9
DOIs
StatePublished - 2012

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