Abstract
Chemical investigation on a Formosan octocoral identified as Briareum sp. has led to the isolation of two new 8-hydroxybriarane diterpenoids, briarenolides H (1) and I (2). The structures of briaranes 1 and 2 were established by spectroscopic methods and by comparison of the spectroscopic data with those of known briarane analogues. Briarenolide H (1) was proven to be the first 6-methoxybriarane derivative. Briarenolide I (2) displayed an inhibitory effect on the generation of superoxide anion by human neutrophils.
Original language | English |
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Pages (from-to) | 1031-1036 |
Number of pages | 6 |
Journal | Bulletin of the Chemical Society of Japan |
Volume | 85 |
Issue number | 9 |
DOIs | |
State | Published - 2012 |