TY - JOUR
T1 - Bullous pemphigoid in a renal transplant recipient
T2 - A case report and review of the literature
AU - Chen, Ting Jui
AU - Lai, Ping Chin
AU - Yang, Li Cheng
AU - Kuo, Tseng Tong
AU - Hon, Hong Shang
PY - 2009
Y1 - 2009
N2 - Bullous pemphigoid (BP) is an autoimmune disease with chronic, recurrent bullous eruptions. BP has been reported to be associated with drugs, physical stimuli, malignancies, and immune abnormalities. Its association with renal transplant is rare and only four cases have been reported. We present a case of BP in a 52-year-old man with chronic hepatitis B and C infection who underwent a cadaveric renal transplant 13 years earlier. His graft was still functioning well when BP appeared. The occurrence of BP in our patient might be a result of drugs (furosemide or tacrolimus), viruses, or renal allograft. As the patient was receiving regular T-cell immunosuppressant therapy, his BP lesions were recalcitrant to corticosteroid treatment. We discuss the pathogenesis and treatment of such patients.
AB - Bullous pemphigoid (BP) is an autoimmune disease with chronic, recurrent bullous eruptions. BP has been reported to be associated with drugs, physical stimuli, malignancies, and immune abnormalities. Its association with renal transplant is rare and only four cases have been reported. We present a case of BP in a 52-year-old man with chronic hepatitis B and C infection who underwent a cadaveric renal transplant 13 years earlier. His graft was still functioning well when BP appeared. The occurrence of BP in our patient might be a result of drugs (furosemide or tacrolimus), viruses, or renal allograft. As the patient was receiving regular T-cell immunosuppressant therapy, his BP lesions were recalcitrant to corticosteroid treatment. We discuss the pathogenesis and treatment of such patients.
UR - http://www.scopus.com/inward/record.url?scp=64749110561&partnerID=8YFLogxK
U2 - 10.2165/00128071-200910030-00007
DO - 10.2165/00128071-200910030-00007
M3 - 文章
C2 - 19354335
AN - SCOPUS:64749110561
SN - 1175-0561
VL - 10
SP - 197
EP - 200
JO - American Journal of Clinical Dermatology
JF - American Journal of Clinical Dermatology
IS - 3
ER -