Abstract
Effects of carbamazepine on alcohol withdrawal seizures and symptoms were studied in rats. Carbamazepine was administered during alcohol feeding and continued during alcohol withdrawal. When carbamazepine serum levels were above 3 pg per milliliter, alcohol withdrawal seizures were not observed. Carbamazepine also alleviated alcohol withdrawal symptoms, especially heightened spontaneous activity, startle to noise, stereotyped chewing movements, and intermittent body stiffening.
| Original language | English |
|---|---|
| Pages (from-to) | 1397-1401 |
| Number of pages | 5 |
| Journal | Neurology |
| Volume | 29 |
| Issue number | 10 |
| DOIs | |
| State | Published - 10 1979 |
| Externally published | Yes |