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Carbon dots for bacterial detection and antibacterial applications-a minireview

  • Anisha Anand
  • , Gopinathan Manavalan
  • , Ranju Prasad Mandal
  • , Huan Tsung Chang
  • , Yi Ru Chiou
  • , Chih Ching Huang*
  • *Corresponding author for this work
  • National Taiwan Ocean University
  • National Taiwan University
  • National Changhua University of Education
  • Kaohsiung Medical University

Research output: Contribution to journalShort surveypeer-review

23 Scopus citations

Abstract

The prevention and treatment of various infections caused by microbes through antibiotics are becoming less effective due to antimicrobial resistance. Researches are focused on antimicrobial nanomaterials to inhibit bacterial growth and destroy the cells, to replace conventional antibiotics. Recently, carbon dots (C-Dots) become attractive candidates for a wide range of applications, including the detection and treatment of pathogens. In addition to low toxicity, ease of synthesis and functionalization, and high biocompatibility, C-Dots show excellent optical properties such as multi-emission, high brightness, and photostability. C-Dots have shown great potential in various fields, such as biosensing, nanomedicine, photo-catalysis, and bioimaging. This review focuses on the origin and synthesis of various C-Dots with special emphasis on bacterial detection, the antibacterial effect of CDots, and their mechanism.

Original languageEnglish
Pages (from-to)4848-4860
Number of pages13
JournalCurrent Pharmaceutical Design
Volume25
Issue number46
DOIs
StatePublished - 2019
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2019 Bentham Science Publishers.

Keywords

  • Antimicrobial activity
  • Bacterial detection
  • Carbon quantum dots
  • Fluorescence
  • Photoactivation
  • Reactive oxygen species

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