Abstract
Salivary uric acid is regarded as a noninvasive biomarker of metabolic syndrome and renal disorder. Although many enzyme based assays have been developed for quantitation of uric acids, most of the biological reagents are only stable for 30 days after opening even stored at 2-8 °C. To overcome this short-lasting problem, long-lasting (more than two years), easily stored and cost-effective nonenzymatic C-dots prepared from PEI through a simple hydrothermal method were developed. Experimental results reveal that the sensitivity of the PEI C-dot assay for uric acid is higher than that of reported fluorescece and enzyme based sensors.
| Original language | English |
|---|---|
| Title of host publication | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 769-772 |
| Number of pages | 4 |
| ISBN (Electronic) | 9781510897571 |
| State | Published - 2018 |
| Externally published | Yes |
| Event | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 - Kaohsiung, Taiwan Duration: 11 11 2018 → 15 11 2018 |
Publication series
| Name | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 |
|---|---|
| Volume | 2 |
Conference
| Conference | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 |
|---|---|
| Country/Territory | Taiwan |
| City | Kaohsiung |
| Period | 11/11/18 → 15/11/18 |
Bibliographical note
Publisher Copyright:Copyright © (2018) by Chemical and Biological Microsystems Society. All rights reserved.
Keywords
- Carbon nanodots
- Photoluminescence
- Polyethylenimine
- Uric acid