Carbon nanodots prepared from polyethylenimine for quantitation of salivary uric acid

  • Wei Cheng Wu
  • , Hsin Yi Tiffany Chen
  • , Shih Chi Lin
  • , Hsin Ying Chen
  • , Fu Rong Chen
  • , Huan Tsung Chang
  • , Fan Gang Tseng*
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Salivary uric acid is regarded as a noninvasive biomarker of metabolic syndrome and renal disorder. Although many enzyme based assays have been developed for quantitation of uric acids, most of the biological reagents are only stable for 30 days after opening even stored at 2-8 °C. To overcome this short-lasting problem, long-lasting (more than two years), easily stored and cost-effective nonenzymatic C-dots prepared from PEI through a simple hydrothermal method were developed. Experimental results reveal that the sensitivity of the PEI C-dot assay for uric acid is higher than that of reported fluorescece and enzyme based sensors.

Original languageEnglish
Title of host publication22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
PublisherChemical and Biological Microsystems Society
Pages769-772
Number of pages4
ISBN (Electronic)9781510897571
StatePublished - 2018
Externally publishedYes
Event22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 - Kaohsiung, Taiwan
Duration: 11 11 201815 11 2018

Publication series

Name22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Volume2

Conference

Conference22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Country/TerritoryTaiwan
CityKaohsiung
Period11/11/1815/11/18

Bibliographical note

Publisher Copyright:
Copyright © (2018) by Chemical and Biological Microsystems Society. All rights reserved.

Keywords

  • Carbon nanodots
  • Photoluminescence
  • Polyethylenimine
  • Uric acid

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