Case report: Recurrent fungal keratitis and blepharitis caused by aspergillus flavus

Chia Yi Lee, Yi Ju Ho, Chi Chin Sun, Hsin Chiung Lin, Ching Hsi Hsiao, David Hui Kang Ma, Chi Chun Lai, Hung Chi Chen*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

8 Scopus citations


Aspergillus species produces a wide spectrum of fungal diseases like endophthalmitis and fungal keratitis ophthalmologically, but there has been no report about blepharitis caused by Aspergilus flavus to date. Herein, we report a 61-year-old ethnic Han Taiwanese male who had suffered from pain with burning and foreign body sensation after an insect bite on his left eye. Specimens from bilateral eyelids suggested infection of A. flavus, whereas corneal scraping showed the presence of Gram-negative bacteria. He was admitted for treatment of infectious keratitis with topical antibiotic and antifungal eye drops. Two weeks after discharge, recurrent blepharitis and keratitis of A. flavus was diagnosed microbiologically. Another treatment course of antifungal agent was resumed in the following 6 months, without further significant symptoms in the following 2 years. Collectively, it is possible for A. flavus to induce concurrent keratitis and blepharitis, and combined treatment of keratitis as well as blepharitis is advocated for as long as 6 months to ensure no recurrence.

Original languageEnglish
Pages (from-to)1216-1218
Number of pages3
JournalAmerican Journal of Tropical Medicine and Hygiene
Issue number5
StatePublished - 11 2016

Bibliographical note

Publisher Copyright:
© 2016 by The American Society of Tropical Medicine and Hygiene.


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