Charge-monitoring laser-induced acoustic desorption mass spectrometry for cell and microparticle mass distribution measurement

Wen Ping Peng; Huan Chang Lin; Hsin Hung Lin; Minglee Chu; Alice L. Yu; Huan Cheng Chang; Chung Hsuan Chen

doi:10.1002/anie.200700309

Charge-monitoring laser-induced acoustic desorption mass spectrometry for cell and microparticle mass distribution measurement

Wen Ping Peng^*
, Huan Chang Lin
, Hsin Hung Lin
, Minglee Chu
, Alice L. Yu
, Huan Cheng Chang
, Chung Hsuan Chen

^*Corresponding author for this work

Academia Sinica - Genomics Research Center
Academia Sinica - Institute of Physics
Academia Sinica - Institute of Atomic and Molecular Sciences

Research output: Contribution to journal › Journal Article › peer-review

60 Scopus citations

Abstract

Mass exodus: A mass spectrometer for the rapid measurement of mass distributions of cells and microparticles is described. A discharge process is used to provide cells with thousands of charges so that direct charge measurement can be achieved. This device was used to measure microparticles with masses as high as 10¹⁵ Da and to distinguish cancer cells from normal cells. (Figure Presented).

Original language	English
Pages (from-to)	3865-3869
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	46
Issue number	21
DOIs	https://doi.org/10.1002/anie.200700309
State	Published - 2007
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cells
Charge detection
Ion trap
Mass spectrometry
Microparticles

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10.1002/anie.200700309

Cite this

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title = "Charge-monitoring laser-induced acoustic desorption mass spectrometry for cell and microparticle mass distribution measurement",

abstract = "Mass exodus: A mass spectrometer for the rapid measurement of mass distributions of cells and microparticles is described. A discharge process is used to provide cells with thousands of charges so that direct charge measurement can be achieved. This device was used to measure microparticles with masses as high as 1015 Da and to distinguish cancer cells from normal cells. (Figure Presented).",

keywords = "Cells, Charge detection, Ion trap, Mass spectrometry, Microparticles",

author = "Peng, \{Wen Ping\} and Lin, \{Huan Chang\} and Lin, \{Hsin Hung\} and Minglee Chu and Yu, \{Alice L.\} and Chang, \{Huan Cheng\} and Chen, \{Chung Hsuan\}",

year = "2007",

doi = "10.1002/anie.200700309",

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volume = "46",

pages = "3865--3869",

journal = "Angewandte Chemie - International Edition",

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TY - JOUR

T1 - Charge-monitoring laser-induced acoustic desorption mass spectrometry for cell and microparticle mass distribution measurement

AU - Peng, Wen Ping

AU - Lin, Huan Chang

AU - Lin, Hsin Hung

AU - Chu, Minglee

AU - Yu, Alice L.

AU - Chang, Huan Cheng

AU - Chen, Chung Hsuan

PY - 2007

Y1 - 2007

N2 - Mass exodus: A mass spectrometer for the rapid measurement of mass distributions of cells and microparticles is described. A discharge process is used to provide cells with thousands of charges so that direct charge measurement can be achieved. This device was used to measure microparticles with masses as high as 1015 Da and to distinguish cancer cells from normal cells. (Figure Presented).

AB - Mass exodus: A mass spectrometer for the rapid measurement of mass distributions of cells and microparticles is described. A discharge process is used to provide cells with thousands of charges so that direct charge measurement can be achieved. This device was used to measure microparticles with masses as high as 1015 Da and to distinguish cancer cells from normal cells. (Figure Presented).

KW - Cells

KW - Charge detection

KW - Ion trap

KW - Mass spectrometry

KW - Microparticles

UR - https://www.scopus.com/pages/publications/34250750204

U2 - 10.1002/anie.200700309

DO - 10.1002/anie.200700309

M3 - 文章

C2 - 17436263

AN - SCOPUS:34250750204

SN - 1433-7851

VL - 46

SP - 3865

EP - 3869

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 21

ER -

Charge-monitoring laser-induced acoustic desorption mass spectrometry for cell and microparticle mass distribution measurement

Abstract

UN SDGs

Keywords

Access to Document

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