Chemical shift magnetic resonance imaging for spectroscopic analysis of biological tissues

Ta Te Lin*, Yu Che Cheng, Jen Fang Yu, Chung Fang Chien

*Corresponding author for this work

Research output: Contribution to conferenceConference Paperpeer-review

Abstract

Magnetic resonance imaging (MRI) has been widely applied in biological research and diagnostics. The chemical shift magnetic resonance imaging technique is a sequence of matrix with one spectroscopic and two spatial dimensions. This technique allows for the determination of chemical composition as well as the spatial information of the specimen and therefore it is an efficient tool to assess internal characteristics of various biological tissues. This paper introduces the process of acquiring chemical shift images of selected biological tissues and the determinations of imaging parameters for spectral images of optimum quality. An image analysis software was developed and image analysis algorithms such as image segmentation, pseudo-color processing, and image fusion were established for the analysis of spectral images. The software allows for displaying the acquired data either as a set spectrum representing the chemical composition of each pixel, or image slices representing the spatial distribution of an individual component. The efficacy of chemical shift imaging is demonstrated in this research with quantitative analysis of lean and fat portions of animal tissues.

Original languageEnglish
Pages4371-4382
Number of pages12
StatePublished - 2004
Externally publishedYes
EventASAE Annual International Meeting 2004 - Ottawa, ON, Canada
Duration: 01 08 200404 08 2004

Conference

ConferenceASAE Annual International Meeting 2004
Country/TerritoryCanada
CityOttawa, ON
Period01/08/0404/08/04

Keywords

  • Chemical shift imaging (CSI)
  • Magnetic resonance imaging (MRI)
  • Spectroscopy

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