Abstract
Stripping crystallization (SC) was applied in this study to purify S-2-phenylpropionic acid (S-2-PPA) from enantiomer mixtures. According to the solid-liquid equilibrium predicted by the Schroder-Van Laar equation and the vapor-liquid equilibrium predicted by Raoult's law, a series of three-phase transformation conditions were determined to perform the batch SC experiments. As opposed to the solid-liquid transformation in melt crystallization, a series of three-phase transformations occur operated at low pressures during the SC cooling process. The experimental yield and purity for the final S-2-PPA product obtained during SC were investigated. A comparison was made between the experimental results and the calculated results based on the material and energy balances.
Original language | English |
---|---|
Pages (from-to) | 10224-10232 |
Number of pages | 9 |
Journal | Industrial and Engineering Chemistry Research |
Volume | 61 |
Issue number | 28 |
DOIs | |
State | Published - 20 07 2022 |
Bibliographical note
Publisher Copyright:© 2022 American Chemical Society. All rights reserved.