Choroidal metastasis from esophageal squamous cell carcinoma

Shin Yu Chang, Shawn Tsai*, Lee Jen Chen, Wei Chun Chan, Yeou Ping Tsao

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

4 Scopus citations


We presented a rare case of a sole choroidal metastatic tumor from esophageal squamous cell carcinoma (ESCC) without other organ metastasis in Taiwan. A 43-year-old male with ESCC was referred for a 1-month history of decreased vision in his left eye. A 5.7 mm thick, yellow choroidal tumor occupied posterior pole, featured with pinpoint hyperfluorescence on angiography and subretinal fluid on optical coherence tomography. Positron emission tomography showed a singular hypermetabolic focus in the left eye. The tumor regressed with complete response and the vision preserved after radiation with total 57.60 gray applied by tomotherapy. The gastrointestinal system is the third most common metastatic origin in Taiwan while esophageal cancer metastasizing to choroid is rare. The discrepancy between the high prevalence of primary ESCC and the rareness of choroidal metastasis from ESCC is undetermined.

Original languageEnglish
Pages (from-to)104-107
Number of pages4
JournalTaiwan Journal of Ophthalmology
Issue number2
StatePublished - 01 04 2018
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2018 Taiwan J Ophthalmol Published by Wolters Kluwer - Medknow.


  • Carcinoma
  • choroid neoplasms
  • esophageal neoplasms
  • neoplasm metastasis
  • squamous cell


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