Chronic manganese intoxication

Chin Chang Huang; Nai Shin Chu; Chin Song Lu; Jung Der Wang; Jin Lian Tsai; Jia Liang Tzeng; Erik C. Wolters; Donald B. Calne

doi:10.1001/archneur.1989.00520460090018

Chronic manganese intoxication

Chin Chang Huang
, Nai Shin Chu
, Chin Song Lu
, Jung Der Wang
, Jin Lian Tsai
, Jia Liang Tzeng
, Erik C. Wolters
, Donald B. Calne

National Taiwan University

Research output: Contribution to journal › Journal Article › peer-review

253 Scopus citations

Abstract

We report six cases of chronic manganese intoxication in workers at a ferromanganese factory in Taiwan. Diagnosis was confirmed by assessing increased manganese concentrations in the blood, scalp, and pubic hair. In addition, increased manganese levels in the environmental air were established. The patients showed a bradykinetic-rigid syndrome indistinguishable from Parkinson's disease that responded to treatment with levodopa.

Original language	English
Pages (from-to)	1104-1106
Number of pages	3
Journal	Archives of Neurology
Volume	46
Issue number	10
DOIs	https://doi.org/10.1001/archneur.1989.00520460090018
State	Published - 10 1989
Externally published	Yes

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10.1001/archneur.1989.00520460090018

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title = "Chronic manganese intoxication",

abstract = "We report six cases of chronic manganese intoxication in workers at a ferromanganese factory in Taiwan. Diagnosis was confirmed by assessing increased manganese concentrations in the blood, scalp, and pubic hair. In addition, increased manganese levels in the environmental air were established. The patients showed a bradykinetic-rigid syndrome indistinguishable from Parkinson's disease that responded to treatment with levodopa.",

author = "Huang, \{Chin Chang\} and Chu, \{Nai Shin\} and Lu, \{Chin Song\} and Wang, \{Jung Der\} and Tsai, \{Jin Lian\} and Tzeng, \{Jia Liang\} and Wolters, \{Erik C.\} and Calne, \{Donald B.\}",

year = "1989",

month = oct,

doi = "10.1001/archneur.1989.00520460090018",

language = "英语",

volume = "46",

pages = "1104--1106",

journal = "Archives of Neurology",

issn = "0003-9942",

publisher = "American Medical Association",

number = "10",

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TY - JOUR

T1 - Chronic manganese intoxication

AU - Huang, Chin Chang

AU - Chu, Nai Shin

AU - Lu, Chin Song

AU - Wang, Jung Der

AU - Tsai, Jin Lian

AU - Tzeng, Jia Liang

AU - Wolters, Erik C.

AU - Calne, Donald B.

PY - 1989/10

Y1 - 1989/10

N2 - We report six cases of chronic manganese intoxication in workers at a ferromanganese factory in Taiwan. Diagnosis was confirmed by assessing increased manganese concentrations in the blood, scalp, and pubic hair. In addition, increased manganese levels in the environmental air were established. The patients showed a bradykinetic-rigid syndrome indistinguishable from Parkinson's disease that responded to treatment with levodopa.

AB - We report six cases of chronic manganese intoxication in workers at a ferromanganese factory in Taiwan. Diagnosis was confirmed by assessing increased manganese concentrations in the blood, scalp, and pubic hair. In addition, increased manganese levels in the environmental air were established. The patients showed a bradykinetic-rigid syndrome indistinguishable from Parkinson's disease that responded to treatment with levodopa.

UR - https://www.scopus.com/pages/publications/0024455148

U2 - 10.1001/archneur.1989.00520460090018

DO - 10.1001/archneur.1989.00520460090018

M3 - 文章

C2 - 2803069

AN - SCOPUS:0024455148

SN - 0003-9942

VL - 46

SP - 1104

EP - 1106

JO - Archives of Neurology

JF - Archives of Neurology

IS - 10

ER -

Chronic manganese intoxication

Abstract

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