Chronic mucocutaneous candidiasis in a 6-year-old boy

Shih Jung Chiu, Ching Hsiung Tsao, Li Chen Chen, Chun Chieh Kao, Ko Huang Lue, Jing Long Huang*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

6 Scopus citations

Abstract

Chronic mucocutaneous candidiasis (CMC) is a complex disorder characterized by persistent or recurrent candidal infections of the skin, nails and/or mucous membranes. A familial occurrence has been reported in some instances, suggesting a genetic predisposition. CMC has also been suggested to be associated with a selective defect in T cell-mediated immunity to Candida antigens. Reports of cases in Asians are rare. We report a case of CMC in a 6-year-old boy with chronic candidal infection since 7 months of age. The patient presented with deficient cell-mediated immunity and decreased natural killer cells. This case highlights the need for detailed studies for evaluating the T-cell immunity in patients with chronic candial infection.

Original languageEnglish
Pages (from-to)196-199
Number of pages4
JournalJournal of Microbiology, Immunology and Infection
Volume37
Issue number3
StatePublished - 06 2004
Externally publishedYes

Keywords

  • Case reports
  • Cellular immunity
  • Chronic mucocutaneous candidiasis
  • Diagnosis

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