Cladielloides C and D: Novel eunicellin-based diterpenoids from an indonesian octocoral cladiella sp.

Chia Ying Tai; Yung Husan Chen; Tsong Long Hwang; Lee Shing Fang; Wei Hsien Wang; Ming Chin Liu; Jui Hsin Su; Yang Chang Wu; Ping Jyun Sung

doi:10.1246/bcsj.20100348

Cladielloides C and D: Novel eunicellin-based diterpenoids from an indonesian octocoral cladiella sp.

Chia Ying Tai^*, Yung Husan Chen, Tsong Long Hwang, Lee Shing Fang, Wei Hsien Wang, Ming Chin Liu, Jui Hsin Su, Yang Chang Wu, Ping Jyun Sung

^*Corresponding author for this work

School of Traditional Chinese Medicine

Research output: Contribution to journal › Journal Article › peer-review

13 Scopus citations

Abstract

Chemical investigation on an Indonesian octocoral identified as Cladiella sp. has led to the isolation of two novel eunicellin-based diterpenoids, cladielloides C (1) and D (2). The structures of 1 and 2 were established by spectroscopic methods. Compound 1 exhibited significant cytotoxicity toward CCRF-CEM tumor cells and metabolites 1 and 2 displayed moderate inhibitory effects on superoxide anion generation by human neutrophils.

Original language	English
Pages (from-to)	531-536
Number of pages	6
Journal	Bulletin of the Chemical Society of Japan
Volume	84
Issue number	5
DOIs	https://doi.org/10.1246/bcsj.20100348
State	Published - 2011

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title = "Cladielloides C and D: Novel eunicellin-based diterpenoids from an indonesian octocoral cladiella sp.",

abstract = "Chemical investigation on an Indonesian octocoral identified as Cladiella sp. has led to the isolation of two novel eunicellin-based diterpenoids, cladielloides C (1) and D (2). The structures of 1 and 2 were established by spectroscopic methods. Compound 1 exhibited significant cytotoxicity toward CCRF-CEM tumor cells and metabolites 1 and 2 displayed moderate inhibitory effects on superoxide anion generation by human neutrophils.",

author = "Tai, \{Chia Ying\} and Chen, \{Yung Husan\} and Hwang, \{Tsong Long\} and Fang, \{Lee Shing\} and Wang, \{Wei Hsien\} and Liu, \{Ming Chin\} and Su, \{Jui Hsin\} and Wu, \{Yang Chang\} and Sung, \{Ping Jyun\}",

year = "2011",

doi = "10.1246/bcsj.20100348",

language = "英语",

volume = "84",

pages = "531--536",

journal = "Bulletin of the Chemical Society of Japan",

issn = "0009-2673",

publisher = "Oxford University Press",

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TY - JOUR

T1 - Cladielloides C and D

T2 - Novel eunicellin-based diterpenoids from an indonesian octocoral cladiella sp.

AU - Tai, Chia Ying

AU - Chen, Yung Husan

AU - Hwang, Tsong Long

AU - Fang, Lee Shing

AU - Wang, Wei Hsien

AU - Liu, Ming Chin

AU - Su, Jui Hsin

AU - Wu, Yang Chang

AU - Sung, Ping Jyun

PY - 2011

Y1 - 2011

N2 - Chemical investigation on an Indonesian octocoral identified as Cladiella sp. has led to the isolation of two novel eunicellin-based diterpenoids, cladielloides C (1) and D (2). The structures of 1 and 2 were established by spectroscopic methods. Compound 1 exhibited significant cytotoxicity toward CCRF-CEM tumor cells and metabolites 1 and 2 displayed moderate inhibitory effects on superoxide anion generation by human neutrophils.

AB - Chemical investigation on an Indonesian octocoral identified as Cladiella sp. has led to the isolation of two novel eunicellin-based diterpenoids, cladielloides C (1) and D (2). The structures of 1 and 2 were established by spectroscopic methods. Compound 1 exhibited significant cytotoxicity toward CCRF-CEM tumor cells and metabolites 1 and 2 displayed moderate inhibitory effects on superoxide anion generation by human neutrophils.

UR - https://www.scopus.com/pages/publications/79956114360

U2 - 10.1246/bcsj.20100348

DO - 10.1246/bcsj.20100348

M3 - 文章

AN - SCOPUS:79956114360

SN - 0009-2673

VL - 84

SP - 531

EP - 536

JO - Bulletin of the Chemical Society of Japan

JF - Bulletin of the Chemical Society of Japan

IS - 5

ER -

Cladielloides C and D: Novel eunicellin-based diterpenoids from an indonesian octocoral cladiella sp.

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