Clinical Characteristics and Risk Factors for Seizures Associated with Norovirus Gastroenteritis in Childhood

Mei Hua Hu, Kuang Lin Lin, Chang Teng Wu, Shih Yen Chen, Go Shine Huang*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

16 Scopus citations

Abstract

Norovirus has become increasingly recognized as causing viral gastroenteritis in children. Few data are available on the characteristics of children admitted to pediatric emergency departments with norovirus gastroenteritis and accompanying seizures. Our aim in this study was to describe the clinical features of, and risk factors for, seizures accompanying norovirus gastroenteritis. We collected 6359 stool samples from patients with gastroenteritis, of whom 1444 (22.71%) had laboratory-confirmed norovirus gastroenteritis. Of all patients, 108 (7.48%) children exhibited norovirus gastroenteritis and seizures; 49 (45.4%) were febrile, and 59 (54.6%) afebrile. The mean patient age was 2.31 ± 2.12 years; most were <5 years of age (92.6%). The afebrile group had a significantly higher incidence of 2 or more seizures than the febrile subjects (P =.004). Early recognition and prompt treatment of convulsions associated with norovirus gastroenteritis in children are important. Future studies might explore the long-term prognoses of these patients.

Original languageEnglish
Pages (from-to)810-814
Number of pages5
JournalJournal of Child Neurology
Volume32
Issue number9
DOIs
StatePublished - 01 08 2017

Bibliographical note

Publisher Copyright:
© SAGE Publications.

Keywords

  • antiepileptic drugs
  • children
  • electroencephalography
  • febrile seizures
  • seizures

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