Clinical characteristics of corticobasal syndrome amongst Chinese in Taiwan

Kuo Hsuan Chang; Chih Ching Chuang; Rong Kuo Lyu; Chiung Mei Chen; Long Sun Ro; Sien Tsong Chen; Yih Ru Wu

doi:10.1016/j.parkreldis.2006.10.003

Clinical characteristics of corticobasal syndrome amongst Chinese in Taiwan

Kuo Hsuan Chang, Chih Ching Chuang, Rong Kuo Lyu, Chiung Mei Chen, Long Sun Ro, Sien Tsong Chen, Yih Ru Wu^*

^*Corresponding author for this work

School of Medicine

Chang Gung University

Research output: Contribution to journal › Journal Article › peer-review

1 Scopus citations

Abstract

This study reviewed the clinical characteristics of nine patients, the female-to-male ratio being 2 (6/3), with corticobasal syndrome (CBS) from 2001 to 2006. The mean age of onset was 60.33±5.20 years. The most popular symptom was rigidity (100%), followed by bradykinesia (88.89%), apraxia (88.89%) and dystonia (66.67%). The common presentations in neuropsychological assessment included frontal dysfunction (88.89%), disorientation (66.67%), memory impairments (66.67%) and visuospecial defects (66.67%). Single proton emission-computed tomography (CT) showed hypoperfusion at contralateral basal ganglia, thalamic, parietal or temporal region in eight of nine patients. This investigation suggests that functional neuroimages and neuropsychological tests are useful tools for the diagnosis of CBS.

Original language	English
Pages (from-to)	219-223
Number of pages	5
Journal	Parkinsonism and Related Disorders
Volume	13
Issue number	4
DOIs	https://doi.org/10.1016/j.parkreldis.2006.10.003
State	Published - 05 2007

Keywords

Corticobasal degeneration
Movement disorders
Parkinsonism

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10.1016/j.parkreldis.2006.10.003

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title = "Clinical characteristics of corticobasal syndrome amongst Chinese in Taiwan",

abstract = "This study reviewed the clinical characteristics of nine patients, the female-to-male ratio being 2 (6/3), with corticobasal syndrome (CBS) from 2001 to 2006. The mean age of onset was 60.33±5.20 years. The most popular symptom was rigidity (100%), followed by bradykinesia (88.89%), apraxia (88.89%) and dystonia (66.67%). The common presentations in neuropsychological assessment included frontal dysfunction (88.89%), disorientation (66.67%), memory impairments (66.67%) and visuospecial defects (66.67%). Single proton emission-computed tomography (CT) showed hypoperfusion at contralateral basal ganglia, thalamic, parietal or temporal region in eight of nine patients. This investigation suggests that functional neuroimages and neuropsychological tests are useful tools for the diagnosis of CBS.",

keywords = "Corticobasal degeneration, Movement disorders, Parkinsonism",

author = "Chang, {Kuo Hsuan} and Chuang, {Chih Ching} and Lyu, {Rong Kuo} and Chen, {Chiung Mei} and Ro, {Long Sun} and Chen, {Sien Tsong} and Wu, {Yih Ru}",

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AU - Chang, Kuo Hsuan

AU - Chuang, Chih Ching

AU - Lyu, Rong Kuo

AU - Chen, Chiung Mei

AU - Ro, Long Sun

AU - Chen, Sien Tsong

AU - Wu, Yih Ru

PY - 2007/5

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N2 - This study reviewed the clinical characteristics of nine patients, the female-to-male ratio being 2 (6/3), with corticobasal syndrome (CBS) from 2001 to 2006. The mean age of onset was 60.33±5.20 years. The most popular symptom was rigidity (100%), followed by bradykinesia (88.89%), apraxia (88.89%) and dystonia (66.67%). The common presentations in neuropsychological assessment included frontal dysfunction (88.89%), disorientation (66.67%), memory impairments (66.67%) and visuospecial defects (66.67%). Single proton emission-computed tomography (CT) showed hypoperfusion at contralateral basal ganglia, thalamic, parietal or temporal region in eight of nine patients. This investigation suggests that functional neuroimages and neuropsychological tests are useful tools for the diagnosis of CBS.

AB - This study reviewed the clinical characteristics of nine patients, the female-to-male ratio being 2 (6/3), with corticobasal syndrome (CBS) from 2001 to 2006. The mean age of onset was 60.33±5.20 years. The most popular symptom was rigidity (100%), followed by bradykinesia (88.89%), apraxia (88.89%) and dystonia (66.67%). The common presentations in neuropsychological assessment included frontal dysfunction (88.89%), disorientation (66.67%), memory impairments (66.67%) and visuospecial defects (66.67%). Single proton emission-computed tomography (CT) showed hypoperfusion at contralateral basal ganglia, thalamic, parietal or temporal region in eight of nine patients. This investigation suggests that functional neuroimages and neuropsychological tests are useful tools for the diagnosis of CBS.

KW - Corticobasal degeneration

KW - Movement disorders

KW - Parkinsonism

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SN - 1353-8020

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ER -

Clinical characteristics of corticobasal syndrome amongst Chinese in Taiwan

Abstract

Keywords

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