Clinical significance of positive treadmill exercise test in patients with mitral stenosis

Lung An Hsu; Cheng Wen Chiang; Chi Jen Chang; Po Hsien Chu; Tsu Shiu Hsu; Yu Lin Ko; Chi Tai Kuo

Clinical significance of positive treadmill exercise test in patients with mitral stenosis

Lung An Hsu^*, Cheng Wen Chiang, Chi Jen Chang, Po Hsien Chu, Tsu Shiu Hsu, Yu Lin Ko, Chi Tai Kuo

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

Abstract

Purpose: This study sought to assess the clinical significance of an exercise stress test (EST) in symptomatic mitral stenosis (MS) patients with sinus rhythm. Methods: Data from 44 consecutive patients with symptomatic MS and sinus rhythm who underwent balloon mitral commissurotomy, a pre-procedural submaximal treadmill test, and coronary angiography were analyzed. Results: Only one patient had angiographically significant coronary artery disease (CAD), but with a negative EST. Ten (23.3%) had positive ESTs, but without angiographically significant CAD. The sensitivity, specificity, positive and negative predictive values of EST for CAD were 0%, 75%, 0% and 97.1%, respectively. There was no association between hemodynamic parameters and a positive EST. Conclusions: False-positive EST is very common in MS patients, and is not related to their hemodynamic characteristics.

Original language	English
Pages (from-to)	160-164
Number of pages	5
Journal	Acta Cardiologica Sinica
Volume	18
Issue number	4
State	Published - 12 2002
Externally published	Yes

Keywords

Coronary artery disease
Mitral stenosis
Treadmill exercise test

Cite this

@article{3069b63825064eef8ca41275fe0babb2,

title = "Clinical significance of positive treadmill exercise test in patients with mitral stenosis",

abstract = "Purpose: This study sought to assess the clinical significance of an exercise stress test (EST) in symptomatic mitral stenosis (MS) patients with sinus rhythm. Methods: Data from 44 consecutive patients with symptomatic MS and sinus rhythm who underwent balloon mitral commissurotomy, a pre-procedural submaximal treadmill test, and coronary angiography were analyzed. Results: Only one patient had angiographically significant coronary artery disease (CAD), but with a negative EST. Ten (23.3%) had positive ESTs, but without angiographically significant CAD. The sensitivity, specificity, positive and negative predictive values of EST for CAD were 0%, 75%, 0% and 97.1%, respectively. There was no association between hemodynamic parameters and a positive EST. Conclusions: False-positive EST is very common in MS patients, and is not related to their hemodynamic characteristics.",

keywords = "Coronary artery disease, Mitral stenosis, Treadmill exercise test",

author = "Hsu, {Lung An} and Chiang, {Cheng Wen} and Chang, {Chi Jen} and Chu, {Po Hsien} and Hsu, {Tsu Shiu} and Ko, {Yu Lin} and Kuo, {Chi Tai}",

year = "2002",

month = dec,

language = "英语",

volume = "18",

pages = "160--164",

journal = "Acta Cardiologica Sinica",

issn = "1011-6842",

publisher = "Republic of China Society of Cardiology",

number = "4",

}

TY - JOUR

T1 - Clinical significance of positive treadmill exercise test in patients with mitral stenosis

AU - Hsu, Lung An

AU - Chiang, Cheng Wen

AU - Chang, Chi Jen

AU - Chu, Po Hsien

AU - Hsu, Tsu Shiu

AU - Ko, Yu Lin

AU - Kuo, Chi Tai

PY - 2002/12

Y1 - 2002/12

N2 - Purpose: This study sought to assess the clinical significance of an exercise stress test (EST) in symptomatic mitral stenosis (MS) patients with sinus rhythm. Methods: Data from 44 consecutive patients with symptomatic MS and sinus rhythm who underwent balloon mitral commissurotomy, a pre-procedural submaximal treadmill test, and coronary angiography were analyzed. Results: Only one patient had angiographically significant coronary artery disease (CAD), but with a negative EST. Ten (23.3%) had positive ESTs, but without angiographically significant CAD. The sensitivity, specificity, positive and negative predictive values of EST for CAD were 0%, 75%, 0% and 97.1%, respectively. There was no association between hemodynamic parameters and a positive EST. Conclusions: False-positive EST is very common in MS patients, and is not related to their hemodynamic characteristics.

AB - Purpose: This study sought to assess the clinical significance of an exercise stress test (EST) in symptomatic mitral stenosis (MS) patients with sinus rhythm. Methods: Data from 44 consecutive patients with symptomatic MS and sinus rhythm who underwent balloon mitral commissurotomy, a pre-procedural submaximal treadmill test, and coronary angiography were analyzed. Results: Only one patient had angiographically significant coronary artery disease (CAD), but with a negative EST. Ten (23.3%) had positive ESTs, but without angiographically significant CAD. The sensitivity, specificity, positive and negative predictive values of EST for CAD were 0%, 75%, 0% and 97.1%, respectively. There was no association between hemodynamic parameters and a positive EST. Conclusions: False-positive EST is very common in MS patients, and is not related to their hemodynamic characteristics.

KW - Coronary artery disease

KW - Mitral stenosis

KW - Treadmill exercise test

UR - http://www.scopus.com/inward/record.url?scp=0037544521&partnerID=8YFLogxK

M3 - 文章

AN - SCOPUS:0037544521

SN - 1011-6842

VL - 18

SP - 160

EP - 164

JO - Acta Cardiologica Sinica

JF - Acta Cardiologica Sinica

IS - 4

ER -

Clinical significance of positive treadmill exercise test in patients with mitral stenosis

Abstract

Keywords

Other files and links

Fingerprint

Cite this