@inproceedings{7b99fc01215140c997aaee9100b0a9d0,
title = "Cnts gated nanofluidic system for single bacterium detection by GNPS-based redox signal amplification",
abstract = "In this work, we report a portable microfluidic chip based on gold nanoparticle-enhanced electrochemical detection for single-bacteria diognostic. The possibility of single-bacteria detection is realized here by using electroactive molecules modified on gold nanoparticles (NPs) to detect and differentiate Staphylococcus aureus and Pseudomonas aeruginosa. The detection limit of these two electroactive molecules is near femtomolar (1 pM) when immobilized on gold nanoparticles (NPs), and the minima amounts of gold NPs required in the detection is around thousands (103 particle/μl). A concentration of couples whole bacteria (<10 cells/μl) is detected by CV measurements. The liner detection limit concention is form 1-1000 cells/μl. The results showed that the portable biochip system has great potential as a device for single-particle or possibly even single-organism detection.",
keywords = "gold nanoparticles, redox signal amplification, single bacteria detection",
author = "Wen, \{Po Chao\} and Wu, \{Ren Guei\} and Chang, \{Hwan You\} and Tseng, \{Fan Gang\}",
year = "2013",
doi = "10.1109/Transducers.2013.6626772",
language = "英语",
isbn = "9781467359818",
series = "2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013",
pages = "341--344",
booktitle = "2013 Transducers and Eurosensors XXVII",
note = "2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013 ; Conference date: 16-06-2013 Through 20-06-2013",
}