Coexistence of hepatoma with mantle cell lymphoma in a hepatitis B carrier

Mu Hsien Lee, Yu Ching Lin, Hao Tsai Cheng*, Wen Yu Chuang, Hsin Chih Huang, Hsiao Wen Kao

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

3 Scopus citations

Abstract

The coexistence of hepatocellular carcinoma (HCC) and non-Hodgkin's lymphoma (NHL) in the liver is rare. Reports show that these patients have cirrhotic livers or hepatitis virus infections before they develop HCC and NHL. We present a patient with hepatitis B virus infection who was transferred to our hospital with a newly detected liver mass; abdominal computed tomography examination showed one hypodense mass of 7 cm in diameter and multiple mesenteric and mediastinal lymph nodes. A liver tumor biopsy showed a hepatoma, and the pathologic findings from an inguinal lymph node excision showed mantle cell lymphoma. An immunohistochemical stain confirmed that the atypical lymphoid cells within the HCC were positive for the CD20, CD5 and cyclin D1 antigens. Taking these findings into account, the hepatic tumor was determined to be a HCC infiltrated by mantle cell lymphoma.

Original languageEnglish
Pages (from-to)12981-12986
Number of pages6
JournalWorld Journal of Gastroenterology
Volume21
Issue number45
DOIs
StatePublished - 07 12 2015

Bibliographical note

Publisher Copyright:
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.

Keywords

  • Hepatitis B virus
  • Hepatocellular carcinoma
  • Mantle cell lymphoma

Fingerprint

Dive into the research topics of 'Coexistence of hepatoma with mantle cell lymphoma in a hepatitis B carrier'. Together they form a unique fingerprint.

Cite this