Color doppler ultrasound in breast carcinomas: Relationship with hormone receptors, DNA ploidy, S-phase fraction, and histopathology

Tzu Chieh Chao; Yung Feng Luo; Shin Cheh Chen; Miin Fu Chen

doi:10.1016/S0301-5629(00)00345-8

Color doppler ultrasound in breast carcinomas: Relationship with hormone receptors, DNA ploidy, S-phase fraction, and histopathology

Tzu Chieh Chao^*, Yung Feng Luo, Shin Cheh Chen, Miin Fu Chen

^*Corresponding author for this work

School of Medicine

Chang Gung University

Research output: Contribution to journal › Journal Article › peer-review

10 Scopus citations

Abstract

Data on 368 patients with breast carcinomas measuring ≤ 5 cm were analyzed to study the relationship between the prognostic factors and the flow indices measured by color Doppler ultrasound (US). Vascularity was detected by color Doppler US in 348 (94.6%) of the 368 breast tumors. Tumors without vascularity were significantly (p = 0.0001) smaller than the tumors with vascularity. There was a correlation between V_max and tumor size. Postmenopausal women had greater values of RI, PI, and V_max. Tumors larger than 2 cm had significantly greater RI, V_max and number of vessels as compared with the tumors smaller than 2 cm. RI was significantly greater in the nondiploid tumors than in the diploid tumors. RI ≥ 0.7 was significantly associated with nondiploid carcinomas and SPF ≥ 7%. Tumor size and V_max significantly predicted axillary lymph node metastases.

Original language	English
Pages (from-to)	351-355
Number of pages	5
Journal	Ultrasound in Medicine and Biology
Volume	27
Issue number	3
DOIs	https://doi.org/10.1016/S0301-5629(00)00345-8
State	Published - 03 2001

Keywords

Breast carcinoma
Color Doppler ultrasound
DNA ploidy
Lymph node
Metastasis
Peak systolic flow velocity
Pulsatility index
Resistance index
S-phase fraction

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10.1016/S0301-5629(00)00345-8

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@article{ef4ce4bc847a4cc5bc699e0bae1963b9,

title = "Color doppler ultrasound in breast carcinomas: Relationship with hormone receptors, DNA ploidy, S-phase fraction, and histopathology",

abstract = "Data on 368 patients with breast carcinomas measuring ≤ 5 cm were analyzed to study the relationship between the prognostic factors and the flow indices measured by color Doppler ultrasound (US). Vascularity was detected by color Doppler US in 348 (94.6%) of the 368 breast tumors. Tumors without vascularity were significantly (p = 0.0001) smaller than the tumors with vascularity. There was a correlation between Vmax and tumor size. Postmenopausal women had greater values of RI, PI, and Vmax. Tumors larger than 2 cm had significantly greater RI, Vmax and number of vessels as compared with the tumors smaller than 2 cm. RI was significantly greater in the nondiploid tumors than in the diploid tumors. RI ≥ 0.7 was significantly associated with nondiploid carcinomas and SPF ≥ 7%. Tumor size and Vmax significantly predicted axillary lymph node metastases.",

keywords = "Breast carcinoma, Color Doppler ultrasound, DNA ploidy, Lymph node, Metastasis, Peak systolic flow velocity, Pulsatility index, Resistance index, S-phase fraction",

author = "Chao, {Tzu Chieh} and Luo, {Yung Feng} and Chen, {Shin Cheh} and Chen, {Miin Fu}",

year = "2001",

month = mar,

doi = "10.1016/S0301-5629(00)00345-8",

language = "英语",

volume = "27",

pages = "351--355",

journal = "Ultrasound in Medicine and Biology",

issn = "0301-5629",

publisher = "Elsevier Inc.",

number = "3",

}

TY - JOUR

T1 - Color doppler ultrasound in breast carcinomas

T2 - Relationship with hormone receptors, DNA ploidy, S-phase fraction, and histopathology

AU - Chao, Tzu Chieh

AU - Luo, Yung Feng

AU - Chen, Shin Cheh

AU - Chen, Miin Fu

PY - 2001/3

Y1 - 2001/3

N2 - Data on 368 patients with breast carcinomas measuring ≤ 5 cm were analyzed to study the relationship between the prognostic factors and the flow indices measured by color Doppler ultrasound (US). Vascularity was detected by color Doppler US in 348 (94.6%) of the 368 breast tumors. Tumors without vascularity were significantly (p = 0.0001) smaller than the tumors with vascularity. There was a correlation between Vmax and tumor size. Postmenopausal women had greater values of RI, PI, and Vmax. Tumors larger than 2 cm had significantly greater RI, Vmax and number of vessels as compared with the tumors smaller than 2 cm. RI was significantly greater in the nondiploid tumors than in the diploid tumors. RI ≥ 0.7 was significantly associated with nondiploid carcinomas and SPF ≥ 7%. Tumor size and Vmax significantly predicted axillary lymph node metastases.

AB - Data on 368 patients with breast carcinomas measuring ≤ 5 cm were analyzed to study the relationship between the prognostic factors and the flow indices measured by color Doppler ultrasound (US). Vascularity was detected by color Doppler US in 348 (94.6%) of the 368 breast tumors. Tumors without vascularity were significantly (p = 0.0001) smaller than the tumors with vascularity. There was a correlation between Vmax and tumor size. Postmenopausal women had greater values of RI, PI, and Vmax. Tumors larger than 2 cm had significantly greater RI, Vmax and number of vessels as compared with the tumors smaller than 2 cm. RI was significantly greater in the nondiploid tumors than in the diploid tumors. RI ≥ 0.7 was significantly associated with nondiploid carcinomas and SPF ≥ 7%. Tumor size and Vmax significantly predicted axillary lymph node metastases.

KW - Breast carcinoma

KW - Color Doppler ultrasound

KW - DNA ploidy

KW - Lymph node

KW - Metastasis

KW - Peak systolic flow velocity

KW - Pulsatility index

KW - Resistance index

KW - S-phase fraction

UR - http://www.scopus.com/inward/record.url?scp=0035014874&partnerID=8YFLogxK

U2 - 10.1016/S0301-5629(00)00345-8

DO - 10.1016/S0301-5629(00)00345-8

M3 - 文章

C2 - 11369120

AN - SCOPUS:0035014874

SN - 0301-5629

VL - 27

SP - 351

EP - 355

JO - Ultrasound in Medicine and Biology

JF - Ultrasound in Medicine and Biology

IS - 3

ER -

Color doppler ultrasound in breast carcinomas: Relationship with hormone receptors, DNA ploidy, S-phase fraction, and histopathology

Abstract

Keywords

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