Combined detection of cancer cells and a tumor biomarker using an immunomagnetic sensor for the improvement of prostate-cancer diagnosis

Hung Wei Yang; Chih Wen Lin; Mu Yi Hua; Shih Sheng Liao; Ying Tzu Chen; Hsiao Chien Chen; Wen Hui Weng; Cheng Keng Chuang; See Tong Pang; Chen Chi M. Ma

doi:10.1002/adma.201305842

Combined detection of cancer cells and a tumor biomarker using an immunomagnetic sensor for the improvement of prostate-cancer diagnosis

Hung Wei Yang, Chih Wen Lin, Mu Yi Hua, Shih Sheng Liao, Ying Tzu Chen, Hsiao Chien Chen, Wen Hui Weng, Cheng Keng Chuang, See Tong Pang^*, Chen Chi M. Ma

^*Corresponding author for this work

Department of Chemical and Materials Engineering

Research output: Contribution to journal › Journal Article › peer-review

40 Scopus citations

Abstract

Capture and detection of both a relevant antigen and cancer cells are demonstrated using magnetic graphene oxide (MGO) possessing conjugated antibodies. By simply dropping the MGO onto the surface of Pt electrodes while in a magnetic field, the sensor is rapidly constructed. The dual approach of the sensor potentially offers a more accurate, rapid platform than current tests based on immunological methods.

Original language	English
Pages (from-to)	3662-3666
Number of pages	5
Journal	Advanced Materials
Volume	26
Issue number	22
DOIs	https://doi.org/10.1002/adma.201305842
State	Published - 11 06 2014

Keywords

biomedical applications
biosensors
diagnostic tools
graphene oxide
magnetic materials
prostate cancer

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/adma.201305842

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title = "Combined detection of cancer cells and a tumor biomarker using an immunomagnetic sensor for the improvement of prostate-cancer diagnosis",

abstract = "Capture and detection of both a relevant antigen and cancer cells are demonstrated using magnetic graphene oxide (MGO) possessing conjugated antibodies. By simply dropping the MGO onto the surface of Pt electrodes while in a magnetic field, the sensor is rapidly constructed. The dual approach of the sensor potentially offers a more accurate, rapid platform than current tests based on immunological methods.",

keywords = "biomedical applications, biosensors, diagnostic tools, graphene oxide, magnetic materials, prostate cancer",

author = "Yang, {Hung Wei} and Lin, {Chih Wen} and Hua, {Mu Yi} and Liao, {Shih Sheng} and Chen, {Ying Tzu} and Chen, {Hsiao Chien} and Weng, {Wen Hui} and Chuang, {Cheng Keng} and Pang, {See Tong} and Ma, {Chen Chi M.}",

year = "2014",

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doi = "10.1002/adma.201305842",

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journal = "Advanced Materials",

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T1 - Combined detection of cancer cells and a tumor biomarker using an immunomagnetic sensor for the improvement of prostate-cancer diagnosis

AU - Yang, Hung Wei

AU - Lin, Chih Wen

AU - Hua, Mu Yi

AU - Liao, Shih Sheng

AU - Chen, Ying Tzu

AU - Chen, Hsiao Chien

AU - Weng, Wen Hui

AU - Chuang, Cheng Keng

AU - Pang, See Tong

AU - Ma, Chen Chi M.

PY - 2014/6/11

Y1 - 2014/6/11

N2 - Capture and detection of both a relevant antigen and cancer cells are demonstrated using magnetic graphene oxide (MGO) possessing conjugated antibodies. By simply dropping the MGO onto the surface of Pt electrodes while in a magnetic field, the sensor is rapidly constructed. The dual approach of the sensor potentially offers a more accurate, rapid platform than current tests based on immunological methods.

AB - Capture and detection of both a relevant antigen and cancer cells are demonstrated using magnetic graphene oxide (MGO) possessing conjugated antibodies. By simply dropping the MGO onto the surface of Pt electrodes while in a magnetic field, the sensor is rapidly constructed. The dual approach of the sensor potentially offers a more accurate, rapid platform than current tests based on immunological methods.

KW - biomedical applications

KW - biosensors

KW - diagnostic tools

KW - graphene oxide

KW - magnetic materials

KW - prostate cancer

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U2 - 10.1002/adma.201305842

DO - 10.1002/adma.201305842

M3 - 文章

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AN - SCOPUS:84902205502

SN - 0935-9648

VL - 26

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EP - 3666

JO - Advanced Materials

JF - Advanced Materials

IS - 22

ER -

Combined detection of cancer cells and a tumor biomarker using an immunomagnetic sensor for the improvement of prostate-cancer diagnosis

Abstract

Keywords

UN SDGs

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