Combined therapy of mitomycin C and Chinese medical herbs on experimental liver cancer.

D. M. Hau*, T. H. Chen, J. F. Cheng, J. S. You

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

4 Scopus citations

Abstract

In this research, ICR male mice were chosen for intrahepatic implantation of sarcoma 180 tumor cells (1 x 10(7)). The mice were randomly divided into various groups 24 hours after implantation. One of the groups was the tumor control, the others were singly or combinedly treated with mitomycin C (MMC) and Shih Chuan-Ta-Pu-Tang (SCTPT) or Shi-Hung-One (SHO). The results revealed that the mortality rate (MR60) in the tumor control was 100% and the mean survival time (MST60) was 21.11 +/- 10.69 days. The best therapeutic effect appeared in the group treated with the combination of MMC and SHO, its MR6o was 55.0% and MST 60 was 47.0 +/- 13.4 days.

Original languageEnglish
Pages (from-to)51-58
Number of pages8
JournalAmerican Journal of Chinese Medicine
Volume21
Issue number1
DOIs
StatePublished - 1993
Externally publishedYes

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