Complex partial status epilepticus as a manifestation of Hashimoto's encephalopathy

Meng Han Tsai, Lien Hui Lee, Shan Der Chen, Cheng Hisen Lu, Ming Tsung Chen, Yao Chung Chuang*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

34 Scopus citations


Epileptic seizures are a frequent manifestation of Hashimoto's encephalopathy. However, status epilepticus associated with Hashimoto's encephalopathy are not well characterized in medical literature. We described here a 16-year-old girl who presented with complex partial status epilepticus associated with elevated anti-thyroid antibodies. Ictal EEG showed lateralized high amplitude rhythmic delta waves over the right hemisphere and ictal single-photon emission computed tomography revealed regional hyperperfusion of the right parietal and temporal lobes. The patient was unresponsive to antiepileptic drug therapy but responded to intravenous steroid treatment. Screening of serum anti-thyroid antibodies for unexplained encephalopathy with epileptic seizures is suggested, as early recognition and prompt steroid treatment may lead to a favorable prognosis.

Original languageEnglish
Pages (from-to)713-716
Number of pages4
Issue number8
StatePublished - 12 2007
Externally publishedYes


  • Complex partial seizure
  • Corticosteroid
  • Hashimoto's encephalopathy
  • Status epilepticus


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