Congenital abnormalities of the conduction system in two patients with tachyarrhythmias

S. Bharati, R. Bauernfiend, M. Scheinman, B. Massie, M. Cheitlin, P. Denes, D. Wu, M. Lev, K. M. Rosen

Research output: Contribution to journalJournal Article peer-review

45 Scopus citations


Serial sections of the conduction system (CS) were performed in two patients with recurrent tachyarrhythmias. Case 1, a 34-year-old female who had dual atrioventricular (AV) nodal pathways with recurrent paroxysmal supraventricular tachycardia, committed suicide. Autopsy revealed an abnormally formed atrial septum with insertion of eustachian valve on the AV part of the pars membranacea. The intercuspid portion of the pars membranacea was muscular. The ASV node was located adjacent to the membranous part of the ventricular septum rather than the central fibrous body. In addition, there was an accessory anterior AV node on the parietal wall of the right atrium. Case 2, a 13-year-old boy with history of recurrent ventricular tachycardia, died suddenly. CS revealed a right-sided, markedly septated bundle. The first part of right bundle branch was divided into three parts, which later joined together. Both cases showed fatty infiltration of the atrial septum, more than normal for the age of the patients. The relationship of the recurrent tachyarrhythmias to the congenital abnormalities in the CS in the two cases and the fatty infiltration is reviewed.

Original languageEnglish
Pages (from-to)593-606
Number of pages14
JournalUnknown Journal
Issue number3
StatePublished - 1979


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