Congenital cytomegalovirus infection in 1 twin with a pericardial effusion: A case report

Fang Ping Chen; Li Fen Teng; Ju Yi Chen; Ning Lee

Congenital cytomegalovirus infection in 1 twin with a pericardial effusion: A case report

Fang Ping Chen^*, Li Fen Teng, Ju Yi Chen, Ning Lee

^*Corresponding author for this work

School of Medicine

Chang Gung Memorial Hospital

Research output: Contribution to journal › Journal Article › peer-review

3 Scopus citations

Abstract

BACKGROUND: Congenital fetal damage related to cytomegalovirus (CMV) infection is largely attributable to maternal primary infection. Twin fetuses may react differently to the same maternal influences. CASE: A woman had a sonographically documented fetal pericardial effusion in 1 twin at 33 weeks of gestation. The workup for maternal infection and fetal structural anomaly was negative except for positive CMV IgG in the maternal serum. Cesarean section was performed due to fetal distress. After delivery, CMV viral antigenemia was found in 1 twin with petechiae, thrombocytopenia, hepatosplenomegaly and ventriculomegaly. The other twin was not infected and in stable condition. CONCLUSION: Since twin fetuses simultaneously exposed to the same maternal influence had a completely different outcome, maternal factors play a limited role in influencing CMV transmission.

Original language	English
Pages (from-to)	317-319
Number of pages	3
Journal	Journal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume	52
Issue number	4
State	Published - 04 2007

Keywords

Congenital disorders
Cytomegalovirus infections
Pericardial effusion
Twins

Cite this

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title = "Congenital cytomegalovirus infection in 1 twin with a pericardial effusion: A case report",

abstract = "BACKGROUND: Congenital fetal damage related to cytomegalovirus (CMV) infection is largely attributable to maternal primary infection. Twin fetuses may react differently to the same maternal influences. CASE: A woman had a sonographically documented fetal pericardial effusion in 1 twin at 33 weeks of gestation. The workup for maternal infection and fetal structural anomaly was negative except for positive CMV IgG in the maternal serum. Cesarean section was performed due to fetal distress. After delivery, CMV viral antigenemia was found in 1 twin with petechiae, thrombocytopenia, hepatosplenomegaly and ventriculomegaly. The other twin was not infected and in stable condition. CONCLUSION: Since twin fetuses simultaneously exposed to the same maternal influence had a completely different outcome, maternal factors play a limited role in influencing CMV transmission.",

keywords = "Congenital disorders, Cytomegalovirus infections, Pericardial effusion, Twins",

author = "Chen, {Fang Ping} and Teng, {Li Fen} and Chen, {Ju Yi} and Ning Lee",

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T1 - Congenital cytomegalovirus infection in 1 twin with a pericardial effusion

T2 - A case report

AU - Chen, Fang Ping

AU - Teng, Li Fen

AU - Chen, Ju Yi

AU - Lee, Ning

PY - 2007/4

Y1 - 2007/4

N2 - BACKGROUND: Congenital fetal damage related to cytomegalovirus (CMV) infection is largely attributable to maternal primary infection. Twin fetuses may react differently to the same maternal influences. CASE: A woman had a sonographically documented fetal pericardial effusion in 1 twin at 33 weeks of gestation. The workup for maternal infection and fetal structural anomaly was negative except for positive CMV IgG in the maternal serum. Cesarean section was performed due to fetal distress. After delivery, CMV viral antigenemia was found in 1 twin with petechiae, thrombocytopenia, hepatosplenomegaly and ventriculomegaly. The other twin was not infected and in stable condition. CONCLUSION: Since twin fetuses simultaneously exposed to the same maternal influence had a completely different outcome, maternal factors play a limited role in influencing CMV transmission.

AB - BACKGROUND: Congenital fetal damage related to cytomegalovirus (CMV) infection is largely attributable to maternal primary infection. Twin fetuses may react differently to the same maternal influences. CASE: A woman had a sonographically documented fetal pericardial effusion in 1 twin at 33 weeks of gestation. The workup for maternal infection and fetal structural anomaly was negative except for positive CMV IgG in the maternal serum. Cesarean section was performed due to fetal distress. After delivery, CMV viral antigenemia was found in 1 twin with petechiae, thrombocytopenia, hepatosplenomegaly and ventriculomegaly. The other twin was not infected and in stable condition. CONCLUSION: Since twin fetuses simultaneously exposed to the same maternal influence had a completely different outcome, maternal factors play a limited role in influencing CMV transmission.

KW - Congenital disorders

KW - Cytomegalovirus infections

KW - Pericardial effusion

KW - Twins

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AN - SCOPUS:34247604562

SN - 0024-7758

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JO - Journal of Reproductive Medicine for the Obstetrician and Gynecologist

JF - Journal of Reproductive Medicine for the Obstetrician and Gynecologist

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ER -

Congenital cytomegalovirus infection in 1 twin with a pericardial effusion: A case report

Abstract

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