Constituents from the stems of Hibiscus taiwanensis

Pei Lin Wu; Tian Shung Wu; Cai Xia He; Chia Hao Su; Kuo Hsiung Lee

doi:10.1248/cpb.53.56

Constituents from the stems of Hibiscus taiwanensis

Pei Lin Wu^*
, Tian Shung Wu
, Cai Xia He
, Chia Hao Su
, Kuo Hsiung Lee

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

46 Scopus citations

Abstract

Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods. Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells. The 9,9′-O-feruloyl-(-)-secoisolaricinresinol (12), myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma.

Original language	English
Pages (from-to)	56-59
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	53
Issue number	1
DOIs	https://doi.org/10.1248/cpb.53.56
State	Published - 01 2005
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Anti-HIV
Cytotoxicity
Hibiscus taiwanensis
Lignan
Malvaceae
Triterpenoid

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10.1248/cpb.53.56

Cite this

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title = "Constituents from the stems of Hibiscus taiwanensis",

abstract = "Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods. Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells. The 9,9′-O-feruloyl-(-)-secoisolaricinresinol (12), myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma.",

keywords = "Anti-HIV, Cytotoxicity, Hibiscus taiwanensis, Lignan, Malvaceae, Triterpenoid",

author = "Wu, \{Pei Lin\} and Wu, \{Tian Shung\} and He, \{Cai Xia\} and Su, \{Chia Hao\} and Lee, \{Kuo Hsiung\}",

year = "2005",

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doi = "10.1248/cpb.53.56",

language = "英语",

volume = "53",

pages = "56--59",

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}

TY - JOUR

T1 - Constituents from the stems of Hibiscus taiwanensis

AU - Wu, Pei Lin

AU - Wu, Tian Shung

AU - He, Cai Xia

AU - Su, Chia Hao

AU - Lee, Kuo Hsiung

PY - 2005/1

Y1 - 2005/1

N2 - Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods. Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells. The 9,9′-O-feruloyl-(-)-secoisolaricinresinol (12), myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma.

AB - Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods. Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells. The 9,9′-O-feruloyl-(-)-secoisolaricinresinol (12), myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma.

KW - Anti-HIV

KW - Cytotoxicity

KW - Hibiscus taiwanensis

KW - Lignan

KW - Malvaceae

KW - Triterpenoid

UR - https://www.scopus.com/pages/publications/18744398777

U2 - 10.1248/cpb.53.56

DO - 10.1248/cpb.53.56

M3 - 文章

C2 - 15635230

AN - SCOPUS:18744398777

SN - 0009-2363

VL - 53

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EP - 59

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 1

ER -

Constituents from the stems of Hibiscus taiwanensis

Abstract

UN SDGs

Keywords

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