Corrected flow time is a good indicator for preload responsiveness during living donor liver donation

B. C. Su, C. F. Luo, W. Y. Chang, W. C. Lee, C. C. Lin*

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

8 Scopus citations


Background Corrected flow time (FTc) has been utilized as preload indicator in recent literature. Accurate estimation of preload status during living donor liver donation (LDLD) is important due to fluid restriction. We evaluate the effectiveness of FTc as a surrogate of preload indicator during LDLD. Materials and Methods Twenty-five patients undergoing LDLD were enrolled in the study. Administration of intravenous fluid was restricted before lobectomy was performed. After the organ was harvest, fluid challenge with 500 mL of Voluven (130/0.42, Fresenius, Friedberg, Germany) was performed. Stroke volume (SV) was measured with ultrasonic cardiac output monitor (USCOM; USCOM Pty, Ltd, Sydney, Australia) before and after the fluid challenge. The FTc value obtained with USCOM before fluid challenge was recorded. Fluid responsiveness was defined as an increase in SV of more than 15%. Receiver operating characteristic (ROC) curve was performed. Results The area under ROC curve was 0.9. The optimal cutoff FTc value was 340 milliseconds during LDLD. Conclusions FTc is a noninvasive, easily obtainable, and essentially good preload indicator during LDLD.

Original languageEnglish
Pages (from-to)672-674
Number of pages3
JournalTransplantation Proceedings
Issue number3
StatePublished - 04 2014


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