Corrigendum to “Leptospira interrogans infection leads to IL-1β and IL-18 secretion from a human macrophage cell line through reactive oxygen species and cathepsin B mediated-NLRP3 inflammasome activation” [Microbe Infect (2018) 254–260] (Microbes and Infection (2018) 20(4) (254–260), (S1286457918300431), (10.1016/j.micinf.2018.01.010))

Shijun Li*, Ming Wang, David M. Ojcius, Bijun Zhou, Weilin Hu, Ying Liu, Qing Ma, Guangpeng Tan, Dingming Wang, Jie Yan*

*Corresponding author for this work

Research output: Contribution to journalComment/debate

2 Scopus citations

Abstract

The authors state that there was a duplication of panels in Figure 4A, which mistakenly took place when they assembled the composite Figure 4A, which contained 18 small panels, during the resubmission process. In the original Figure 4A, the Wild type/2 h panel is identical to the Scramble siRNA/1 h panel and the Wild type/24 h panel is identical to the Scramble siRNA/24 h panel. In this corrected version of Figure 4, Scramble siRNA/1 h panel and the Scramble siRNA/24 h panel of the Figure 4A are replaced with the corresponding representative image, respectively. The Figure 4A in the study aimed to show that siRNA significantly decreased the NLRP3 expression but the scramble siRNA (control siRNA) did not significantly decrease the NLRP3 expression in THP-1 cells. Scramble siRNA control was used to verify the effectiveness of NLRP3 siRNA in the NLRP3 expression. The authors are convinced that the mistake in the placement of the panel does not affect the interpretation of this experiment nor the conclusion of the study. The authors would like to note that the only changes are to the panels of Fig 4A scramble siRNA 1 h and Fig 4A scramble siRNA 24 h, and the rest of the figures are identical to the original published version. The authors apologize to the Editors of journal Microbe and Infection and to the readership for any inconvenience caused.[Formula

Original languageEnglish
Article number104756
JournalMicrobes and Infection
Volume23
Issue number1
DOIs
StatePublished - 01 01 2021
Externally publishedYes

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