TY - JOUR
T1 - Current advances in the biological activity of polysaccharides in dendrobium with intriguing therapeutic potential
AU - Lee, Chun Ting
AU - Kuo, Heng Chun
AU - Chen, Yung Hsiang
AU - Tsai, Ming Yen
N1 - Publisher Copyright:
© 2018 Bentham Science Publishers.
PY - 2018
Y1 - 2018
N2 - The polysaccharides in many plants are attracting worldwide attention because of their biological activities and medical properties, such as anti-viral, anti-oxidative, antichronic inflammation, anti-hypertensive, immunomodulation, and neuron-protective effects, as well as anti-tumor activity. Denodrobium species, a genus of the family orchidaceae, have been used as herbal medicines for hundreds of years in China due to their pharmacological effects. These effects include nourishing the Yin, supplementing the stomach, increasing body fluids, and clearing heat. Recently, numerous researchers have investigated possible active compounds in Denodrobium species, such as lectins, phenanthrenes, alkaloids, trigonopol A, and polysaccharides. Unlike those of other plants, the biological effects of polysaccharides in Dendrobium are a novel research field. In this review, we focus on these novel findings to give readers an overall picture of the intriguing therapeutic potential of polysaccharides in Dendrobium, especially those of the four commonly-used Denodrobium species: D. huoshanense, D. offininale, D. nobile, and D. chrysotoxum.
AB - The polysaccharides in many plants are attracting worldwide attention because of their biological activities and medical properties, such as anti-viral, anti-oxidative, antichronic inflammation, anti-hypertensive, immunomodulation, and neuron-protective effects, as well as anti-tumor activity. Denodrobium species, a genus of the family orchidaceae, have been used as herbal medicines for hundreds of years in China due to their pharmacological effects. These effects include nourishing the Yin, supplementing the stomach, increasing body fluids, and clearing heat. Recently, numerous researchers have investigated possible active compounds in Denodrobium species, such as lectins, phenanthrenes, alkaloids, trigonopol A, and polysaccharides. Unlike those of other plants, the biological effects of polysaccharides in Dendrobium are a novel research field. In this review, we focus on these novel findings to give readers an overall picture of the intriguing therapeutic potential of polysaccharides in Dendrobium, especially those of the four commonly-used Denodrobium species: D. huoshanense, D. offininale, D. nobile, and D. chrysotoxum.
KW - Antioxidants
KW - Biological effects
KW - Chinese herb medicine
KW - Dendrobium
KW - Natural products
KW - Polysaccharides
UR - http://www.scopus.com/inward/record.url?scp=85041118145&partnerID=8YFLogxK
U2 - 10.2174/0929867324666170227114648
DO - 10.2174/0929867324666170227114648
M3 - 文献综述
C2 - 28245766
AN - SCOPUS:85041118145
SN - 0929-8673
VL - 25
SP - 1663
EP - 1681
JO - Current Medicinal Chemistry
JF - Current Medicinal Chemistry
IS - 14
ER -