Current Understanding of the Molecular Basis of Spices for the Development of Potential Antimicrobial Medicine

Purnima Khatri, Asha Rani, Saif Hameed, Subhash Chandra, Chung Ming Chang*, Ramendra Pati Pandey*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations

Abstract

Antimicrobial resistance increases day by day around the world. To overcome this situation new antimicrobial agents are needed. Spices such as clove, ginger, coriander, garlic, and turmeric have the potential to fight resistant microbes. Due to their therapeutic properties, medicinal herbs and spices have been utilized as herbal medicines since antiquity. They are important sources of organic antibacterial substances that are employed in treating infectious disorders caused by pathogens such as bacteria. The main focus of the study is the bioactivity of the active ingredients present in different kinds of naturally available spices. We conducted a thorough search of PubMed, Google Scholar, and Research Gate for this review. We have read many kinds of available literature, and in this paper, we conclude that many different kinds of naturally available spices perform some form of bioactivity. After reading several papers, we found that some spices have good antimicrobial and antifungal properties, which may help in controlling the emerging antimicrobial resistance and improving human health. Spices have many phytochemicals, which show good antimicrobial and antifungal effects. This review of the literature concludes that the natural bioactivate compounds present in spices can be used as a drug to overcome antimicrobial resistance in human beings.

Original languageEnglish
Article number270
JournalAntibiotics
Volume12
Issue number2
DOIs
StatePublished - 29 01 2023

Bibliographical note

Publisher Copyright:
© 2023 by the authors.

Keywords

  • antibacterial
  • antifungal
  • antimicrobial resistance
  • phytochemical
  • spices

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