Cytokine activation of natural killer cells

Syh Jae Lin; Pei Tzu Lee; Ming Ling Kuo

doi:10.1007/978-1-4939-0345-0_19

Cytokine activation of natural killer cells

Syh Jae Lin^*
, Pei Tzu Lee
, Ming Ling Kuo

^*Corresponding author for this work

Department of Microbiology and Immunology

Chang Gung Memorial Hospital

Research output: Contribution to journal › Journal Article › peer-review

2 Scopus citations

Abstract

CD3CD56+ natural killer (NK) cells can kill various tumors in a non major histocompatibility complex (MHC)-restricted fashion. Recent advances have been made in the application of NK cells for the treatment of patients with acute myelogenous leukemia (AML). Allogeneic donor-derived NK cells can be activated in vitro and infused into patients receiving stem cell transplants. We describe in this chapter the method to activate NK cells with cytokines and to ascertain their degree of activation.

Original language	English
Pages (from-to)	223-229
Number of pages	7
Journal	Methods in Molecular Biology
Volume	1139
DOIs	https://doi.org/10.1007/978-1-4939-0345-0_19
State	Published - 2014

Bibliographical note

Publisher Copyright:
© Springer Science+Business Media New York 2014.

Keywords

Cytokines
Interleukin-15
Natural killer cells

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/978-1-4939-0345-0_19

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title = "Cytokine activation of natural killer cells",

abstract = "CD3CD56+ natural killer (NK) cells can kill various tumors in a non major histocompatibility complex (MHC)-restricted fashion. Recent advances have been made in the application of NK cells for the treatment of patients with acute myelogenous leukemia (AML). Allogeneic donor-derived NK cells can be activated in vitro and infused into patients receiving stem cell transplants. We describe in this chapter the method to activate NK cells with cytokines and to ascertain their degree of activation.",

keywords = "Cytokines, Interleukin-15, Natural killer cells",

author = "Lin, \{Syh Jae\} and Lee, \{Pei Tzu\} and Kuo, \{Ming Ling\}",

note = "Publisher Copyright: {\textcopyright} Springer Science+Business Media New York 2014.",

year = "2014",

doi = "10.1007/978-1-4939-0345-0\_19",

language = "英语",

volume = "1139",

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journal = "Methods in Molecular Biology",

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T1 - Cytokine activation of natural killer cells

AU - Lin, Syh Jae

AU - Lee, Pei Tzu

AU - Kuo, Ming Ling

N1 - Publisher Copyright: © Springer Science+Business Media New York 2014.

PY - 2014

Y1 - 2014

N2 - CD3CD56+ natural killer (NK) cells can kill various tumors in a non major histocompatibility complex (MHC)-restricted fashion. Recent advances have been made in the application of NK cells for the treatment of patients with acute myelogenous leukemia (AML). Allogeneic donor-derived NK cells can be activated in vitro and infused into patients receiving stem cell transplants. We describe in this chapter the method to activate NK cells with cytokines and to ascertain their degree of activation.

AB - CD3CD56+ natural killer (NK) cells can kill various tumors in a non major histocompatibility complex (MHC)-restricted fashion. Recent advances have been made in the application of NK cells for the treatment of patients with acute myelogenous leukemia (AML). Allogeneic donor-derived NK cells can be activated in vitro and infused into patients receiving stem cell transplants. We describe in this chapter the method to activate NK cells with cytokines and to ascertain their degree of activation.

KW - Cytokines

KW - Interleukin-15

KW - Natural killer cells

UR - https://www.scopus.com/pages/publications/84909581704

U2 - 10.1007/978-1-4939-0345-0_19

DO - 10.1007/978-1-4939-0345-0_19

M3 - 文章

C2 - 24619683

AN - SCOPUS:84909581704

SN - 1064-3745

VL - 1139

SP - 223

EP - 229

JO - Methods in Molecular Biology

JF - Methods in Molecular Biology

ER -

Cytokine activation of natural killer cells

Abstract

Bibliographical note

Keywords

UN SDGs

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