Cytotoxic constituents of Polyalthia longifolia var. pendula

Chung Yi Chen; Fang Rong Chang; Yao Ching Shih; Tian Jye Hsieh; Yi Chen Chia; Huang Yi Tseng; Hua Chien Chen; Shu Jen Chen; Ming Chu Hsu; Yang Chang Wu

doi:10.1021/np000176e

Cytotoxic constituents of Polyalthia longifolia var. pendula

Chung Yi Chen, Fang Rong Chang, Yao Ching Shih, Tian Jye Hsieh, Yi Chen Chia, Huang Yi Tseng, Hua Chien Chen, Shu Jen Chen, Ming Chu Hsu, Yang Chang Wu^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

109 Scopus citations

Abstract

A new halimane diterpene, 3β,5β,16α-trihydroxyhalima-13(14)-en-15,16-olide (1), and a new oxoprotoberberine alkaloid, (-)-8-oxopolyalthiaine (2), along with 20 known compounds, were isolated from a methanolic extract of Polyalthia longifolia var. pendula. The structures of compounds 1 and 2 were established by spectroscopic analysis. Several of these compounds were evaluated for cytotoxicity toward a small panel of human cell lines.

Original language	English
Pages (from-to)	1475-1478
Number of pages	4
Journal	Journal of Natural Products
Volume	63
Issue number	11
DOIs	https://doi.org/10.1021/np000176e
State	Published - 2000
Externally published	Yes

Access to Document

10.1021/np000176e

Cite this

@article{c91d47049ecf4ca2a812e171f8cb2545,

title = "Cytotoxic constituents of Polyalthia longifolia var. pendula",

abstract = "A new halimane diterpene, 3β,5β,16α-trihydroxyhalima-13(14)-en-15,16-olide (1), and a new oxoprotoberberine alkaloid, (-)-8-oxopolyalthiaine (2), along with 20 known compounds, were isolated from a methanolic extract of Polyalthia longifolia var. pendula. The structures of compounds 1 and 2 were established by spectroscopic analysis. Several of these compounds were evaluated for cytotoxicity toward a small panel of human cell lines.",

author = "Chen, {Chung Yi} and Chang, {Fang Rong} and Shih, {Yao Ching} and Hsieh, {Tian Jye} and Chia, {Yi Chen} and Tseng, {Huang Yi} and Chen, {Hua Chien} and Chen, {Shu Jen} and Hsu, {Ming Chu} and Wu, {Yang Chang}",

year = "2000",

doi = "10.1021/np000176e",

language = "英语",

volume = "63",

pages = "1475--1478",

journal = "Journal of Natural Products",

issn = "0163-3864",

publisher = "American Chemical Society",

number = "11",

}

TY - JOUR

T1 - Cytotoxic constituents of Polyalthia longifolia var. pendula

AU - Chen, Chung Yi

AU - Chang, Fang Rong

AU - Shih, Yao Ching

AU - Hsieh, Tian Jye

AU - Chia, Yi Chen

AU - Tseng, Huang Yi

AU - Chen, Hua Chien

AU - Chen, Shu Jen

AU - Hsu, Ming Chu

AU - Wu, Yang Chang

PY - 2000

Y1 - 2000

N2 - A new halimane diterpene, 3β,5β,16α-trihydroxyhalima-13(14)-en-15,16-olide (1), and a new oxoprotoberberine alkaloid, (-)-8-oxopolyalthiaine (2), along with 20 known compounds, were isolated from a methanolic extract of Polyalthia longifolia var. pendula. The structures of compounds 1 and 2 were established by spectroscopic analysis. Several of these compounds were evaluated for cytotoxicity toward a small panel of human cell lines.

AB - A new halimane diterpene, 3β,5β,16α-trihydroxyhalima-13(14)-en-15,16-olide (1), and a new oxoprotoberberine alkaloid, (-)-8-oxopolyalthiaine (2), along with 20 known compounds, were isolated from a methanolic extract of Polyalthia longifolia var. pendula. The structures of compounds 1 and 2 were established by spectroscopic analysis. Several of these compounds were evaluated for cytotoxicity toward a small panel of human cell lines.

UR - http://www.scopus.com/inward/record.url?scp=17544369643&partnerID=8YFLogxK

U2 - 10.1021/np000176e

DO - 10.1021/np000176e

M3 - 文章

C2 - 11087586

AN - SCOPUS:17544369643

SN - 0163-3864

VL - 63

SP - 1475

EP - 1478

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 11

ER -

Cytotoxic constituents of Polyalthia longifolia var. pendula

Abstract

Access to Document

Other files and links

Fingerprint

Cite this