Delayed hypokalemic paralysis following a convulsion due to alcohol abstinence

Wei Hsi Chen; Hsin Ling Yin; Hung Sheng Lin; Shun Sheng Chen; Jia Shou Liu

doi:10.1016/j.jocn.2005.04.032

Delayed hypokalemic paralysis following a convulsion due to alcohol abstinence

Wei Hsi Chen, Hsin Ling Yin, Hung Sheng Lin, Shun Sheng Chen, Jia Shou Liu^*

^*Corresponding author for this work

Chang Gung Memorial Hospital

Research output: Contribution to journal › Journal Article › peer-review

7 Scopus citations

Abstract

We encountered three patients with hypokalemic paralysis following a convulsion in the early stages of alcohol abstinence. The transtubular potassium gradient was less than 2.0, suggesting intracellular potassium shift. Hypokalaemic paralysis may result from retention of intracellular cationic potassium bound by anionic phosphorylated compounds, precipitated by an acceleration of the Na⁺-K⁺ pump in alcohol withdrawal and convulsions. These findings warn of the lethal hypokalemia that may occur after convulsions, particularly soon after alcohol abstinence associated with moderate withdrawal symptoms.

Original language	English
Pages (from-to)	453-456
Number of pages	4
Journal	Journal of Clinical Neuroscience
Volume	13
Issue number	4
DOIs	https://doi.org/10.1016/j.jocn.2005.04.032
State	Published - 05 2006
Externally published	Yes

Keywords

Alcohol
Catecholamine
Convulsion
Hypokalaemic paralysis
Potassium

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10.1016/j.jocn.2005.04.032

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title = "Delayed hypokalemic paralysis following a convulsion due to alcohol abstinence",

abstract = "We encountered three patients with hypokalemic paralysis following a convulsion in the early stages of alcohol abstinence. The transtubular potassium gradient was less than 2.0, suggesting intracellular potassium shift. Hypokalaemic paralysis may result from retention of intracellular cationic potassium bound by anionic phosphorylated compounds, precipitated by an acceleration of the Na+-K+ pump in alcohol withdrawal and convulsions. These findings warn of the lethal hypokalemia that may occur after convulsions, particularly soon after alcohol abstinence associated with moderate withdrawal symptoms.",

keywords = "Alcohol, Catecholamine, Convulsion, Hypokalaemic paralysis, Potassium",

author = "Chen, {Wei Hsi} and Yin, {Hsin Ling} and Lin, {Hung Sheng} and Chen, {Shun Sheng} and Liu, {Jia Shou}",

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T1 - Delayed hypokalemic paralysis following a convulsion due to alcohol abstinence

AU - Chen, Wei Hsi

AU - Yin, Hsin Ling

AU - Lin, Hung Sheng

AU - Chen, Shun Sheng

AU - Liu, Jia Shou

PY - 2006/5

Y1 - 2006/5

N2 - We encountered three patients with hypokalemic paralysis following a convulsion in the early stages of alcohol abstinence. The transtubular potassium gradient was less than 2.0, suggesting intracellular potassium shift. Hypokalaemic paralysis may result from retention of intracellular cationic potassium bound by anionic phosphorylated compounds, precipitated by an acceleration of the Na+-K+ pump in alcohol withdrawal and convulsions. These findings warn of the lethal hypokalemia that may occur after convulsions, particularly soon after alcohol abstinence associated with moderate withdrawal symptoms.

AB - We encountered three patients with hypokalemic paralysis following a convulsion in the early stages of alcohol abstinence. The transtubular potassium gradient was less than 2.0, suggesting intracellular potassium shift. Hypokalaemic paralysis may result from retention of intracellular cationic potassium bound by anionic phosphorylated compounds, precipitated by an acceleration of the Na+-K+ pump in alcohol withdrawal and convulsions. These findings warn of the lethal hypokalemia that may occur after convulsions, particularly soon after alcohol abstinence associated with moderate withdrawal symptoms.

KW - Alcohol

KW - Catecholamine

KW - Convulsion

KW - Hypokalaemic paralysis

KW - Potassium

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M3 - 文章

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SN - 0967-5868

VL - 13

SP - 453

EP - 456

JO - Journal of Clinical Neuroscience

JF - Journal of Clinical Neuroscience

IS - 4

ER -

Delayed hypokalemic paralysis following a convulsion due to alcohol abstinence

Abstract

Keywords

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