Detection-ability evaluation of the PEImager for positron emission mammography applications

Meei Ling Jan*, Yu Ching Ni, Keh Shih Chuang, Hsing Ching Liang, Ying Kai Fu

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

2 Scopus citations

Abstract

This work is a pilot study of using a dual-head scanner in positron emission mammography (PEM). A positron emission imager (PEImager) developed at our laboratory was used as a PEM prototype to obtain data. Dual-head projection imaging mode was used in the PEM study. An iterative algebraic reconstruction was employed to reconstruct projection data to obtain tomograms. A cylindrical phantom filled with water was applied to simulate a breast and five hollow spheres (2 mm - 10 mm diameters) filled with F-18-fluoride simulated tumors in the breast phantom. Preliminary data revealed that the locations and sizes of the hot spots in the breast phantom were determined from the reconstructed images. The ability to detect the tumor embedded in the radioactive water was evaluated. At a tumor-to-normal tissue ratio 20:1, a 3 mm tumor was detected; 5 mm and 10 mm tumors could be detected at the ratios of 10:1 and 5:1, respectively.

Original languageEnglish
Pages (from-to)109-113
Number of pages5
JournalPhysica Medica
Volume21
Issue numberSUPPL. 1
DOIs
StatePublished - 2006
Externally publishedYes

Keywords

  • Mammography
  • PEM
  • Positron emission mammography

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