Detection of flufenamic acid based on affordable inorganic SrFe₂O₄ nanorods decorated sulfur atoms substituted graphitic carbon nitride nanocomposite

Generally, the nanoparticle along with the nanosheet architecture has excellent physiochemical properties at the interface of electrode and electrolyte. In this work, the SrFe₂O₄ nanorod was prepared through the simple hydrothermal method, as well as the S-GCN prepared (urea + thiourea) by thermal polymerization, and using the solvent evaporation process SrFe₂O₄ nanorod was decorated on the S-GCN nanosheet, which is used for the electrochemical detection of flufenamic acid (FFA). The electrocatalytic activity of the bare GCE was enhanced by the SrFe₂O₄/S-GCN because SrFe₂O₄ has more active sides and S-GCN has a large surface area which is confirmed by the EIS and CV analysis. Moreover, the synergistic effect between SrFe₂O₄ nanorods and the S-GCN nanosheet provides the fast electron transfer property and enhanced electrocatalytic activity towards the FFA. Our proposed sensor exposed the lower level of the detection limit of 0.004 µM and the linear range of 0.01–384 µM with the LOQ of 0.015 µM. Furthermore, satisfactory recovery results were obtained while using the SrFe₂O₄/S-GCN modified electrode in the human urine and blood serum samples. Hence further development of our proposed SrFe₂O₄/S-GCN sensor will reduce the human health risk from FFA.