Abstract
The polymerase chain reaction was used to test 18 adults and eight fetuses with numerical or structural X-chromosome abnormalities for the presence of nine Y-specific loci. Y-chromosomal DNA was detectable in one adult patient with X-chromosome mosaicism. This study and previous reports provide evidence to support further screening of patients with X-chromosome abnormalities for the presence of Y-chromosomal DNA sequences. Long-term follow-up of patients with Y-chromosomal sequences is required to determine the risk of gonadal neoplasms and other abnormal phenotypes.
| Original language | English |
|---|---|
| Pages (from-to) | 529-534 |
| Number of pages | 6 |
| Journal | Journal of the Formosan Medical Association |
| Volume | 94 |
| Issue number | 9 |
| State | Published - 1995 |
| Externally published | Yes |