Development of arylhydrazines and diphenyl arylhydrazidophosphates as photo-induced DNA-cleaving agents

Jih Ru Hwu*, Chii Shyang Yau, Fu Yuan Tsai, Shwu Chen Tsay

*Corresponding author for this work

Research output: Contribution to journalJournal Article peer-review

4 Scopus citations

Abstract

Single-strand cleavage of DNA in a sodium phosphate buffer at pH 7.4 has been accomplished by photolysis of various arylhydrazines or diphenyl arylhydrazidophosphates with 312 nm UV light; the new processes involve the generation of HO and singlet oxygen, respectively.

Original languageEnglish
Pages (from-to)2451-2453
Number of pages3
JournalJournal of the Chemical Society - Perkin Transactions 1
Issue number17
DOIs
StatePublished - 07 09 1997
Externally publishedYes

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