Development of arylhydrazines and diphenyl arylhydrazidophosphates as photo-induced DNA-cleaving agents

Jih Ru Hwu; Chii Shyang Yau; Fu Yuan Tsai; Shwu Chen Tsay

doi:10.1039/a704706a

Development of arylhydrazines and diphenyl arylhydrazidophosphates as photo-induced DNA-cleaving agents

Jih Ru Hwu^*
, Chii Shyang Yau
, Fu Yuan Tsai
, Shwu Chen Tsay

^*Corresponding author for this work

National Tsing Hua University
Academia Sinica - Institute of Chemistry

Research output: Contribution to journal › Journal Article › peer-review

5 Scopus citations

Abstract

Single-strand cleavage of DNA in a sodium phosphate buffer at pH 7.4 has been accomplished by photolysis of various arylhydrazines or diphenyl arylhydrazidophosphates with 312 nm UV light; the new processes involve the generation of HO^• and singlet oxygen, respectively.

Original language	English
Pages (from-to)	2451-2453
Number of pages	3
Journal	Journal of the Chemical Society - Perkin Transactions 1
Issue number	17
DOIs	https://doi.org/10.1039/a704706a
State	Published - 07 09 1997
Externally published	Yes

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@article{c56194b2dad34ff3afb12afa340e0715,

title = "Development of arylhydrazines and diphenyl arylhydrazidophosphates as photo-induced DNA-cleaving agents",

abstract = "Single-strand cleavage of DNA in a sodium phosphate buffer at pH 7.4 has been accomplished by photolysis of various arylhydrazines or diphenyl arylhydrazidophosphates with 312 nm UV light; the new processes involve the generation of HO• and singlet oxygen, respectively.",

author = "Hwu, \{Jih Ru\} and Yau, \{Chii Shyang\} and Tsai, \{Fu Yuan\} and Tsay, \{Shwu Chen\}",

year = "1997",

month = sep,

day = "7",

doi = "10.1039/a704706a",

language = "英语",

pages = "2451--2453",

journal = "Journal of the Chemical Society - Perkin Transactions 1",

issn = "0300-922X",

publisher = "Royal Society of Chemistry",

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T1 - Development of arylhydrazines and diphenyl arylhydrazidophosphates as photo-induced DNA-cleaving agents

AU - Hwu, Jih Ru

AU - Yau, Chii Shyang

AU - Tsai, Fu Yuan

AU - Tsay, Shwu Chen

PY - 1997/9/7

Y1 - 1997/9/7

N2 - Single-strand cleavage of DNA in a sodium phosphate buffer at pH 7.4 has been accomplished by photolysis of various arylhydrazines or diphenyl arylhydrazidophosphates with 312 nm UV light; the new processes involve the generation of HO• and singlet oxygen, respectively.

AB - Single-strand cleavage of DNA in a sodium phosphate buffer at pH 7.4 has been accomplished by photolysis of various arylhydrazines or diphenyl arylhydrazidophosphates with 312 nm UV light; the new processes involve the generation of HO• and singlet oxygen, respectively.

UR - https://www.scopus.com/pages/publications/33748724069

U2 - 10.1039/a704706a

DO - 10.1039/a704706a

M3 - 文章

AN - SCOPUS:33748724069

SN - 0300-922X

SP - 2451

EP - 2453

JO - Journal of the Chemical Society - Perkin Transactions 1

JF - Journal of the Chemical Society - Perkin Transactions 1

IS - 17

ER -

Development of arylhydrazines and diphenyl arylhydrazidophosphates as photo-induced DNA-cleaving agents

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