Different viral aetiology of hepatocellular carcinoma between two hepatitis B and C endemic townships in Taiwan

Sheng Nan Lu; Pay Yu Chue; Hui Chi Chen; Mei Huei Wu; I. Lung Chen; Jee Fu Huang; Jing Houng Wang; Chien Fang Peng; Ching Hua Shih; San Lin You; Chih Feng Lu; Chien Jen Chen; Wen Yu Chang

doi:10.1111/j.1440-1746.1997.tb00482.x

Different viral aetiology of hepatocellular carcinoma between two hepatitis B and C endemic townships in Taiwan

Sheng Nan Lu^*, Pay Yu Chue, Hui Chi Chen, Mei Huei Wu, I. Lung Chen, Jee Fu Huang, Jing Houng Wang, Chien Fang Peng, Ching Hua Shih, San Lin You, Chih Feng Lu, Chien Jen Chen, Wen Yu Chang

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

55 Scopus citations

Abstract

In Taiwan, we found two hepatitis B virus (HBV)- and hepatitis C virus (HCV)-endemic townships, Paisha and Tzukuan, with an anti-HCV prevalence of 19 and 37% in men, and 26 and 38% in women, respectively. The hepatitis B surface antigen (HBsAg)-positive rates were 25 and 18%, for men and women in Paisha, and 25 and 22% in Tzukuan, respectively. According to the national death certification database (1982 to 1991), the annual age-adjusted mortality rates per 100 000 population for liver cancer among men and women were 83.0 and 13.8, respectively, in Paisha, and 55.9 and 17.0 in Tzukuan compared with 30.9 and 9.1 in Taiwan as a whole. The male-to-female ratios were 6.0 in Paisha and 3.3 in Tzukuan. Aetiology of 11 cases of hepatocellular carcinoma (HCC) from Paisha and 14 cases from Tzukuan were analysed. All HCC cases from Paisha were HBsAg positive, while 13/14 HCC cases from Tzukuan were anti-HCV positive. The endemic duration of HCV in Tzukuan seemed long enough to induce HCC, but the HCV appeared to be a newly introduced infection in Paisha.

Original language	English
Pages (from-to)	547-550
Number of pages	4
Journal	Journal of Gastroenterology and Hepatology (Australia)
Volume	12
Issue number	7
DOIs	https://doi.org/10.1111/j.1440-1746.1997.tb00482.x
State	Published - 1997
Externally published	Yes

Keywords

Hepatitis B virus
Hepatitis C virus
Hepatocellular carcinoma

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1440-1746.1997.tb00482.x

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Lu, S. N., Chue, P. Y., Chen, H. C., Wu, M. H., Chen, I. L., Huang, J. F., Wang, J. H., Peng, C. F., Shih, C. H., You, S. L., Lu, C. F., Chen, C. J., & Chang, W. Y. (1997). Different viral aetiology of hepatocellular carcinoma between two hepatitis B and C endemic townships in Taiwan. Journal of Gastroenterology and Hepatology (Australia), 12(7), 547-550. https://doi.org/10.1111/j.1440-1746.1997.tb00482.x

@article{cf5b4b1b1ffd4d6f8c28584f6b454650,

title = "Different viral aetiology of hepatocellular carcinoma between two hepatitis B and C endemic townships in Taiwan",

abstract = "In Taiwan, we found two hepatitis B virus (HBV)- and hepatitis C virus (HCV)-endemic townships, Paisha and Tzukuan, with an anti-HCV prevalence of 19 and 37% in men, and 26 and 38% in women, respectively. The hepatitis B surface antigen (HBsAg)-positive rates were 25 and 18%, for men and women in Paisha, and 25 and 22% in Tzukuan, respectively. According to the national death certification database (1982 to 1991), the annual age-adjusted mortality rates per 100 000 population for liver cancer among men and women were 83.0 and 13.8, respectively, in Paisha, and 55.9 and 17.0 in Tzukuan compared with 30.9 and 9.1 in Taiwan as a whole. The male-to-female ratios were 6.0 in Paisha and 3.3 in Tzukuan. Aetiology of 11 cases of hepatocellular carcinoma (HCC) from Paisha and 14 cases from Tzukuan were analysed. All HCC cases from Paisha were HBsAg positive, while 13/14 HCC cases from Tzukuan were anti-HCV positive. The endemic duration of HCV in Tzukuan seemed long enough to induce HCC, but the HCV appeared to be a newly introduced infection in Paisha.",

keywords = "Hepatitis B virus, Hepatitis C virus, Hepatocellular carcinoma",

author = "Lu, {Sheng Nan} and Chue, {Pay Yu} and Chen, {Hui Chi} and Wu, {Mei Huei} and Chen, {I. Lung} and Huang, {Jee Fu} and Wang, {Jing Houng} and Peng, {Chien Fang} and Shih, {Ching Hua} and You, {San Lin} and Lu, {Chih Feng} and Chen, {Chien Jen} and Chang, {Wen Yu}",

year = "1997",

doi = "10.1111/j.1440-1746.1997.tb00482.x",

language = "英语",

volume = "12",

pages = "547--550",

journal = "Journal of Gastroenterology and Hepatology (Australia)",

issn = "0815-9319",

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Lu, SN, Chue, PY, Chen, HC, Wu, MH, Chen, IL, Huang, JF, Wang, JH, Peng, CF, Shih, CH, You, SL, Lu, CF, Chen, CJ & Chang, WY 1997, 'Different viral aetiology of hepatocellular carcinoma between two hepatitis B and C endemic townships in Taiwan', Journal of Gastroenterology and Hepatology (Australia), vol. 12, no. 7, pp. 547-550. https://doi.org/10.1111/j.1440-1746.1997.tb00482.x

TY - JOUR

T1 - Different viral aetiology of hepatocellular carcinoma between two hepatitis B and C endemic townships in Taiwan

AU - Lu, Sheng Nan

AU - Chue, Pay Yu

AU - Chen, Hui Chi

AU - Wu, Mei Huei

AU - Chen, I. Lung

AU - Huang, Jee Fu

AU - Wang, Jing Houng

AU - Peng, Chien Fang

AU - Shih, Ching Hua

AU - You, San Lin

AU - Lu, Chih Feng

AU - Chen, Chien Jen

AU - Chang, Wen Yu

PY - 1997

Y1 - 1997

N2 - In Taiwan, we found two hepatitis B virus (HBV)- and hepatitis C virus (HCV)-endemic townships, Paisha and Tzukuan, with an anti-HCV prevalence of 19 and 37% in men, and 26 and 38% in women, respectively. The hepatitis B surface antigen (HBsAg)-positive rates were 25 and 18%, for men and women in Paisha, and 25 and 22% in Tzukuan, respectively. According to the national death certification database (1982 to 1991), the annual age-adjusted mortality rates per 100 000 population for liver cancer among men and women were 83.0 and 13.8, respectively, in Paisha, and 55.9 and 17.0 in Tzukuan compared with 30.9 and 9.1 in Taiwan as a whole. The male-to-female ratios were 6.0 in Paisha and 3.3 in Tzukuan. Aetiology of 11 cases of hepatocellular carcinoma (HCC) from Paisha and 14 cases from Tzukuan were analysed. All HCC cases from Paisha were HBsAg positive, while 13/14 HCC cases from Tzukuan were anti-HCV positive. The endemic duration of HCV in Tzukuan seemed long enough to induce HCC, but the HCV appeared to be a newly introduced infection in Paisha.

AB - In Taiwan, we found two hepatitis B virus (HBV)- and hepatitis C virus (HCV)-endemic townships, Paisha and Tzukuan, with an anti-HCV prevalence of 19 and 37% in men, and 26 and 38% in women, respectively. The hepatitis B surface antigen (HBsAg)-positive rates were 25 and 18%, for men and women in Paisha, and 25 and 22% in Tzukuan, respectively. According to the national death certification database (1982 to 1991), the annual age-adjusted mortality rates per 100 000 population for liver cancer among men and women were 83.0 and 13.8, respectively, in Paisha, and 55.9 and 17.0 in Tzukuan compared with 30.9 and 9.1 in Taiwan as a whole. The male-to-female ratios were 6.0 in Paisha and 3.3 in Tzukuan. Aetiology of 11 cases of hepatocellular carcinoma (HCC) from Paisha and 14 cases from Tzukuan were analysed. All HCC cases from Paisha were HBsAg positive, while 13/14 HCC cases from Tzukuan were anti-HCV positive. The endemic duration of HCV in Tzukuan seemed long enough to induce HCC, but the HCV appeared to be a newly introduced infection in Paisha.

KW - Hepatitis B virus

KW - Hepatitis C virus

KW - Hepatocellular carcinoma

UR - http://www.scopus.com/inward/record.url?scp=8544249123&partnerID=8YFLogxK

U2 - 10.1111/j.1440-1746.1997.tb00482.x

DO - 10.1111/j.1440-1746.1997.tb00482.x

M3 - 文章

AN - SCOPUS:8544249123

SN - 0815-9319

VL - 12

SP - 547

EP - 550

JO - Journal of Gastroenterology and Hepatology (Australia)

JF - Journal of Gastroenterology and Hepatology (Australia)

IS - 7

ER -

Different viral aetiology of hepatocellular carcinoma between two hepatitis B and C endemic townships in Taiwan

Abstract

Keywords

UN SDGs

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