Discovery of novel diterpenoids from Sinularia arborea

Kuan Hua Chen; Chang Feng Dai; Tsong Long Hwang; Chun Yu Chen; Jan Jung Li; Jih Jung Chen; Yang Chang Wu; Jyh Horng Sheu; Wei Hsien Wang; Ping Jyun Sung

doi:10.3390/md12010385

Discovery of novel diterpenoids from Sinularia arborea

Kuan Hua Chen
, Chang Feng Dai
, Tsong Long Hwang
, Chun Yu Chen
, Jan Jung Li
, Jih Jung Chen
, Yang Chang Wu
, Jyh Horng Sheu
, Wei Hsien Wang
, Ping Jyun Sung^*

^*Corresponding author for this work

School of Traditional Chinese Medicine

National Dong Hwa University
National Museum of Marine Biology and Aquarium, Taiwan
National Taiwan University
Chang Gung Memorial Hospital
Chang Gung University
Tajen University
China Medical University Taichung
National Sun Yat-sen University
Kaohsiung Medical University

Research output: Contribution to journal › Journal Article › peer-review

11 Scopus citations

Abstract

Two novel diterpenoids, sinularbols A (1) and B (2), which were found to possess a new carbon skeleton were isolated from the soft coral Sinularia arborea. The structures of compounds 1 and 2 were elucidated by spectroscopic methods and 2 displayed a moderately inhibitory effect on the generation of superoxide anion by human neutrophils.

Original language	English
Pages (from-to)	385-393
Number of pages	9
Journal	Marine Drugs
Volume	12
Issue number	1
DOIs	https://doi.org/10.3390/md12010385
State	Published - 01 2014

Keywords

Diterpenoid
Sinularbol
Sinularborane
Sinularia arborea
Superoxide anion

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10.3390/md12010385

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title = "Discovery of novel diterpenoids from Sinularia arborea",

abstract = "Two novel diterpenoids, sinularbols A (1) and B (2), which were found to possess a new carbon skeleton were isolated from the soft coral Sinularia arborea. The structures of compounds 1 and 2 were elucidated by spectroscopic methods and 2 displayed a moderately inhibitory effect on the generation of superoxide anion by human neutrophils.",

keywords = "Diterpenoid, Sinularbol, Sinularborane, Sinularia arborea, Superoxide anion",

author = "Chen, \{Kuan Hua\} and Dai, \{Chang Feng\} and Hwang, \{Tsong Long\} and Chen, \{Chun Yu\} and Li, \{Jan Jung\} and Chen, \{Jih Jung\} and Wu, \{Yang Chang\} and Sheu, \{Jyh Horng\} and Wang, \{Wei Hsien\} and Sung, \{Ping Jyun\}",

year = "2014",

month = jan,

doi = "10.3390/md12010385",

language = "英语",

volume = "12",

pages = "385--393",

journal = "Marine Drugs",

issn = "1660-3397",

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TY - JOUR

T1 - Discovery of novel diterpenoids from Sinularia arborea

AU - Chen, Kuan Hua

AU - Dai, Chang Feng

AU - Hwang, Tsong Long

AU - Chen, Chun Yu

AU - Li, Jan Jung

AU - Chen, Jih Jung

AU - Wu, Yang Chang

AU - Sheu, Jyh Horng

AU - Wang, Wei Hsien

AU - Sung, Ping Jyun

PY - 2014/1

Y1 - 2014/1

N2 - Two novel diterpenoids, sinularbols A (1) and B (2), which were found to possess a new carbon skeleton were isolated from the soft coral Sinularia arborea. The structures of compounds 1 and 2 were elucidated by spectroscopic methods and 2 displayed a moderately inhibitory effect on the generation of superoxide anion by human neutrophils.

AB - Two novel diterpenoids, sinularbols A (1) and B (2), which were found to possess a new carbon skeleton were isolated from the soft coral Sinularia arborea. The structures of compounds 1 and 2 were elucidated by spectroscopic methods and 2 displayed a moderately inhibitory effect on the generation of superoxide anion by human neutrophils.

KW - Diterpenoid

KW - Sinularbol

KW - Sinularborane

KW - Sinularia arborea

KW - Superoxide anion

UR - https://www.scopus.com/pages/publications/84892857019

U2 - 10.3390/md12010385

DO - 10.3390/md12010385

M3 - 文章

C2 - 24445307

AN - SCOPUS:84892857019

SN - 1660-3397

VL - 12

SP - 385

EP - 393

JO - Marine Drugs

JF - Marine Drugs

IS - 1

ER -

Discovery of novel diterpenoids from Sinularia arborea

Abstract

Keywords

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