Discovery of novel diterpenoids from Sinularia arborea

Kuan Hua Chen; Chang Feng Dai; Tsong Long Hwang; Chun Yu Chen; Jan Jung Li; Jih Jung Chen; Yang Chang Wu; Jyh Horng Sheu; Wei Hsien Wang; Ping Jyun Sung

doi:10.3390/md12010385

Discovery of novel diterpenoids from Sinularia arborea

Kuan Hua Chen
, Chang Feng Dai
, Tsong Long Hwang
, Chun Yu Chen
, Jan Jung Li
, Jih Jung Chen
, Yang Chang Wu
, Jyh Horng Sheu
, Wei Hsien Wang
, Ping Jyun Sung^*

^*Corresponding author for this work

School of Traditional Chinese Medicine

Research output: Contribution to journal › Journal Article › peer-review

11 Scopus citations

Abstract

Two novel diterpenoids, sinularbols A (1) and B (2), which were found to possess a new carbon skeleton were isolated from the soft coral Sinularia arborea. The structures of compounds 1 and 2 were elucidated by spectroscopic methods and 2 displayed a moderately inhibitory effect on the generation of superoxide anion by human neutrophils.

Original language	English
Pages (from-to)	385-393
Number of pages	9
Journal	Marine Drugs
Volume	12
Issue number	1
DOIs	https://doi.org/10.3390/md12010385
State	Published - 01 2014

Keywords

Diterpenoid
Sinularbol
Sinularborane
Sinularia arborea
Superoxide anion

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10.3390/md12010385

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title = "Discovery of novel diterpenoids from Sinularia arborea",

abstract = "Two novel diterpenoids, sinularbols A (1) and B (2), which were found to possess a new carbon skeleton were isolated from the soft coral Sinularia arborea. The structures of compounds 1 and 2 were elucidated by spectroscopic methods and 2 displayed a moderately inhibitory effect on the generation of superoxide anion by human neutrophils.",

keywords = "Diterpenoid, Sinularbol, Sinularborane, Sinularia arborea, Superoxide anion",

author = "Chen, \{Kuan Hua\} and Dai, \{Chang Feng\} and Hwang, \{Tsong Long\} and Chen, \{Chun Yu\} and Li, \{Jan Jung\} and Chen, \{Jih Jung\} and Wu, \{Yang Chang\} and Sheu, \{Jyh Horng\} and Wang, \{Wei Hsien\} and Sung, \{Ping Jyun\}",

year = "2014",

month = jan,

doi = "10.3390/md12010385",

language = "英语",

volume = "12",

pages = "385--393",

journal = "Marine Drugs",

issn = "1660-3397",

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TY - JOUR

T1 - Discovery of novel diterpenoids from Sinularia arborea

AU - Chen, Kuan Hua

AU - Dai, Chang Feng

AU - Hwang, Tsong Long

AU - Chen, Chun Yu

AU - Li, Jan Jung

AU - Chen, Jih Jung

AU - Wu, Yang Chang

AU - Sheu, Jyh Horng

AU - Wang, Wei Hsien

AU - Sung, Ping Jyun

PY - 2014/1

Y1 - 2014/1

N2 - Two novel diterpenoids, sinularbols A (1) and B (2), which were found to possess a new carbon skeleton were isolated from the soft coral Sinularia arborea. The structures of compounds 1 and 2 were elucidated by spectroscopic methods and 2 displayed a moderately inhibitory effect on the generation of superoxide anion by human neutrophils.

AB - Two novel diterpenoids, sinularbols A (1) and B (2), which were found to possess a new carbon skeleton were isolated from the soft coral Sinularia arborea. The structures of compounds 1 and 2 were elucidated by spectroscopic methods and 2 displayed a moderately inhibitory effect on the generation of superoxide anion by human neutrophils.

KW - Diterpenoid

KW - Sinularbol

KW - Sinularborane

KW - Sinularia arborea

KW - Superoxide anion

UR - https://www.scopus.com/pages/publications/84892857019

U2 - 10.3390/md12010385

DO - 10.3390/md12010385

M3 - 文章

C2 - 24445307

AN - SCOPUS:84892857019

SN - 1660-3397

VL - 12

SP - 385

EP - 393

JO - Marine Drugs

JF - Marine Drugs

IS - 1

ER -

Discovery of novel diterpenoids from Sinularia arborea

Abstract

Keywords

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