Distribution of type A and type B EBV in normal individuals and patients with head and neck carcinomas in Taiwan

C. H. Shu; Y. S. Chang; C. L. Liang; S. T. Liu; C. Z. Lin; P. Chang

doi:10.1016/0166-0934(92)90175-D

Distribution of type A and type B EBV in normal individuals and patients with head and neck carcinomas in Taiwan

C. H. Shu^*, Y. S. Chang, C. L. Liang, S. T. Liu, C. Z. Lin, P. Chang

^*Corresponding author for this work

Research output: Contribution to journal › Journal Article › peer-review

13 Scopus citations

Abstract

The subtypes of Epstein-Barr virus (EBV) according to the EBNA 2 gene were investigated in Taiwan by the polymerase chain reaction (PCR) and by Southern blot hybridization. The materials included 53 nasopharyngeal carcinoma (NPC) biopsies, 49 other head and neck cancers and 32 throat washings of normal individuals. EBV DNA was found in all NPC biopsies, 27 of 49 other head and neck carcinomas and 81% of normal individuals. Type A EBV was the predominant type of EBV in both normal individuals and patients with head and neck carcinomas in Taiwan. Type B EBV or coexistence of the A and B types comprised a small number of samples in this study.

Original language	English
Pages (from-to)	123-130
Number of pages	8
Journal	Journal of Virological Methods
Volume	38
Issue number	1
DOIs	https://doi.org/10.1016/0166-0934(92)90175-D
State	Published - 07 1992

Keywords

EBNA 2
Epstein-Barr virus
Nasopharyngeal carcinoma
Polymerase chain reaction

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10.1016/0166-0934(92)90175-D

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title = "Distribution of type A and type B EBV in normal individuals and patients with head and neck carcinomas in Taiwan",

abstract = "The subtypes of Epstein-Barr virus (EBV) according to the EBNA 2 gene were investigated in Taiwan by the polymerase chain reaction (PCR) and by Southern blot hybridization. The materials included 53 nasopharyngeal carcinoma (NPC) biopsies, 49 other head and neck cancers and 32 throat washings of normal individuals. EBV DNA was found in all NPC biopsies, 27 of 49 other head and neck carcinomas and 81% of normal individuals. Type A EBV was the predominant type of EBV in both normal individuals and patients with head and neck carcinomas in Taiwan. Type B EBV or coexistence of the A and B types comprised a small number of samples in this study.",

keywords = "EBNA 2, Epstein-Barr virus, Nasopharyngeal carcinoma, Polymerase chain reaction",

author = "Shu, {C. H.} and Chang, {Y. S.} and Liang, {C. L.} and Liu, {S. T.} and Lin, {C. Z.} and P. Chang",

year = "1992",

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T1 - Distribution of type A and type B EBV in normal individuals and patients with head and neck carcinomas in Taiwan

AU - Shu, C. H.

AU - Chang, Y. S.

AU - Liang, C. L.

AU - Liu, S. T.

AU - Lin, C. Z.

AU - Chang, P.

PY - 1992/7

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N2 - The subtypes of Epstein-Barr virus (EBV) according to the EBNA 2 gene were investigated in Taiwan by the polymerase chain reaction (PCR) and by Southern blot hybridization. The materials included 53 nasopharyngeal carcinoma (NPC) biopsies, 49 other head and neck cancers and 32 throat washings of normal individuals. EBV DNA was found in all NPC biopsies, 27 of 49 other head and neck carcinomas and 81% of normal individuals. Type A EBV was the predominant type of EBV in both normal individuals and patients with head and neck carcinomas in Taiwan. Type B EBV or coexistence of the A and B types comprised a small number of samples in this study.

AB - The subtypes of Epstein-Barr virus (EBV) according to the EBNA 2 gene were investigated in Taiwan by the polymerase chain reaction (PCR) and by Southern blot hybridization. The materials included 53 nasopharyngeal carcinoma (NPC) biopsies, 49 other head and neck cancers and 32 throat washings of normal individuals. EBV DNA was found in all NPC biopsies, 27 of 49 other head and neck carcinomas and 81% of normal individuals. Type A EBV was the predominant type of EBV in both normal individuals and patients with head and neck carcinomas in Taiwan. Type B EBV or coexistence of the A and B types comprised a small number of samples in this study.

KW - EBNA 2

KW - Epstein-Barr virus

KW - Nasopharyngeal carcinoma

KW - Polymerase chain reaction

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JO - Journal of Virological Methods

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Distribution of type A and type B EBV in normal individuals and patients with head and neck carcinomas in Taiwan

Abstract

Keywords

UN SDGs

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