DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing

Chia Chen Chang; Chie Pein Chen; Chen Yu Chen; Chii Wann Lin

doi:10.1039/c6cc01238h

DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing

Chia Chen Chang
, Chie Pein Chen
, Chen Yu Chen^*
, Chii Wann Lin

^*Corresponding author for this work

National Taiwan University
Mackay Memorial Hospital Taiwan

Research output: Contribution to journal › Journal Article › peer-review

37 Scopus citations

Abstract

A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy. The detection limit of 2.3 pM is at least one order of magnitude lower than that of established fibronectin biosensors.

Original language	English
Pages (from-to)	4167-4170
Number of pages	4
Journal	Chemical Communications
Volume	52
Issue number	22
DOIs	https://doi.org/10.1039/c6cc01238h
State	Published - 18 03 2016
Externally published	Yes

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry 2016.

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10.1039/c6cc01238h

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title = "DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing",

abstract = "A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy. The detection limit of 2.3 pM is at least one order of magnitude lower than that of established fibronectin biosensors.",

author = "Chang, \{Chia Chen\} and Chen, \{Chie Pein\} and Chen, \{Chen Yu\} and Lin, \{Chii Wann\}",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2016.",

year = "2016",

month = mar,

day = "18",

doi = "10.1039/c6cc01238h",

language = "英语",

volume = "52",

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T1 - DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing

AU - Chang, Chia Chen

AU - Chen, Chie Pein

AU - Chen, Chen Yu

AU - Lin, Chii Wann

PY - 2016/3/18

Y1 - 2016/3/18

N2 - A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy. The detection limit of 2.3 pM is at least one order of magnitude lower than that of established fibronectin biosensors.

AB - A label-free and enzyme-free colorimetric sensing platform for the amplified detection of fibronectin was developed based on an ingenious combination of catalytic hairpin assembly and a base stacking hybridization-based gold nanoparticle aggregation strategy. The detection limit of 2.3 pM is at least one order of magnitude lower than that of established fibronectin biosensors.

UR - https://www.scopus.com/pages/publications/84960510262

U2 - 10.1039/c6cc01238h

DO - 10.1039/c6cc01238h

M3 - 文章

C2 - 26906691

AN - SCOPUS:84960510262

SN - 1359-7345

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SP - 4167

EP - 4170

JO - Chemical Communications

JF - Chemical Communications

IS - 22

ER -

DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing

Abstract

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