Abstract
A urease-deficient derivative of Streptococcus salivarius 57.I was constructed by allelic exchange at the ureC locus. The wild-type strain was protected against acid killing through hydrolysis of physiologically relevant concentrations of urea, whereas the mutant was not. Also, S. salivarius could use urea as a source of nitrogen for growth exclusively through a urease- dependent pathway.
| Original language | English |
|---|---|
| Pages (from-to) | 4667-4669 |
| Number of pages | 3 |
| Journal | Journal of Bacteriology |
| Volume | 182 |
| Issue number | 16 |
| DOIs | |
| State | Published - 08 2000 |
| Externally published | Yes |