@inproceedings{4d117826f17d4203b13fd08d3aaa525e,
title = "Dynamic embryo culture on a digital microfluidic chip",
abstract = "Embryo culture on a digital microfluidic Chip is presented. The digital microfluidic chip consists of two parallel glass plates with conductive., dielectric., and hydrophobic coatings. ICR mouse embryos are cultivated in the culture media (KSOM AA) droplets placed in a petri dish for static studies or between the parallel glass plates for dynamic studies. Embryo culture is successful with the conductive ITO., dielectric SU-8 2002., hydrophobic Teflon layers., and surfactant Pluronic F127 used in the digital microfluidic devices. Moreover., the blastocyst rate of the embryos cultivated in encapsulated droplets containing culture media core droplets and appropriate culture oil shells is comparable to that of the embryos cultivated in traditional petri dishes. Electrowetting-on-dielectric (EWOD) effectively actuates the investigated encapsulated droplets that will be used for dynamic embryo culture.",
keywords = "Digital microfluidics, Electrowetting-on-dielectric (EWOD), Embryo culture",
author = "Li, {Chun Chao} and Hsu, {Yao Wen} and Huang, {Hong Yuan} and Fan, {Shih Kang}",
year = "2012",
doi = "10.1109/NANOMED.2012.6509124",
language = "英语",
isbn = "9781467351027",
series = "IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED",
pages = "74--77",
booktitle = "NANOMED 2012 - 6th IEEE International Conference on Nano/Molecular Medicine and Engineering",
note = "6th IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2012 ; Conference date: 04-11-2012 Through 07-11-2012",
}