Ectopic ACTH syndrome due to thymic carcinoid tumor in a girl

Kuang Lin Lin; Chen Yin Chen; Hsun Hui Hsu; Pan Fu Kao; Miau Ju Huang; Huei Shyong Wang

doi:10.1515/JPEM.1999.12.4.573

Ectopic ACTH syndrome due to thymic carcinoid tumor in a girl

Kuang Lin Lin
, Chen Yin Chen
, Hsun Hui Hsu
, Pan Fu Kao
, Miau Ju Huang
, Huei Shyong Wang^*

^*Corresponding author for this work

Chang Gung Memorial Hospital

Research output: Contribution to journal › Journal Article › peer-review

22 Scopus citations

Abstract

An 8 year-old girl had a cushingold appearance for six months. Hormone study showed extremely high serum levels of cortisol (>60 μg/dl) and adrenocorticotropic hormone (930 pg/ml). Initial chest X-ray showed nothing unusual, but a technetium-99mm MIBI scan showed an accumulation lesion in the left upper chest cavity. Chest magnetic resonance imaging demonstrated that the mass was in the superior anterior mediastinum. She had complete removal of the tumor with partial thymectomy. The pathology revealed a thymic carcinoid tumor. Carcinoid tumors of the thymus are extremely rare in children and they usually present with Cushing's syndrome. To our knowledge, this is the youngest patient who has ever been reported with this disease.

Original language	English
Pages (from-to)	573-578
Number of pages	6
Journal	Journal of Pediatric Endocrinology and Metabolism
Volume	12
Issue number	4
DOIs	https://doi.org/10.1515/JPEM.1999.12.4.573
State	Published - 1999

Keywords

Cushing's syndrome
Ectopic ACTH
Thymic carcinoid

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10.1515/JPEM.1999.12.4.573

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title = "Ectopic ACTH syndrome due to thymic carcinoid tumor in a girl",

abstract = "An 8 year-old girl had a cushingold appearance for six months. Hormone study showed extremely high serum levels of cortisol (>60 μg/dl) and adrenocorticotropic hormone (930 pg/ml). Initial chest X-ray showed nothing unusual, but a technetium-99mm MIBI scan showed an accumulation lesion in the left upper chest cavity. Chest magnetic resonance imaging demonstrated that the mass was in the superior anterior mediastinum. She had complete removal of the tumor with partial thymectomy. The pathology revealed a thymic carcinoid tumor. Carcinoid tumors of the thymus are extremely rare in children and they usually present with Cushing's syndrome. To our knowledge, this is the youngest patient who has ever been reported with this disease.",

keywords = "Cushing's syndrome, Ectopic ACTH, Thymic carcinoid",

author = "Lin, \{Kuang Lin\} and Chen, \{Chen Yin\} and Hsu, \{Hsun Hui\} and Kao, \{Pan Fu\} and Huang, \{Miau Ju\} and Wang, \{Huei Shyong\}",

year = "1999",

doi = "10.1515/JPEM.1999.12.4.573",

language = "英语",

volume = "12",

pages = "573--578",

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publisher = "Walter de Gruyter GmbH",

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TY - JOUR

T1 - Ectopic ACTH syndrome due to thymic carcinoid tumor in a girl

AU - Lin, Kuang Lin

AU - Chen, Chen Yin

AU - Hsu, Hsun Hui

AU - Kao, Pan Fu

AU - Huang, Miau Ju

AU - Wang, Huei Shyong

PY - 1999

Y1 - 1999

N2 - An 8 year-old girl had a cushingold appearance for six months. Hormone study showed extremely high serum levels of cortisol (>60 μg/dl) and adrenocorticotropic hormone (930 pg/ml). Initial chest X-ray showed nothing unusual, but a technetium-99mm MIBI scan showed an accumulation lesion in the left upper chest cavity. Chest magnetic resonance imaging demonstrated that the mass was in the superior anterior mediastinum. She had complete removal of the tumor with partial thymectomy. The pathology revealed a thymic carcinoid tumor. Carcinoid tumors of the thymus are extremely rare in children and they usually present with Cushing's syndrome. To our knowledge, this is the youngest patient who has ever been reported with this disease.

AB - An 8 year-old girl had a cushingold appearance for six months. Hormone study showed extremely high serum levels of cortisol (>60 μg/dl) and adrenocorticotropic hormone (930 pg/ml). Initial chest X-ray showed nothing unusual, but a technetium-99mm MIBI scan showed an accumulation lesion in the left upper chest cavity. Chest magnetic resonance imaging demonstrated that the mass was in the superior anterior mediastinum. She had complete removal of the tumor with partial thymectomy. The pathology revealed a thymic carcinoid tumor. Carcinoid tumors of the thymus are extremely rare in children and they usually present with Cushing's syndrome. To our knowledge, this is the youngest patient who has ever been reported with this disease.

KW - Cushing's syndrome

KW - Ectopic ACTH

KW - Thymic carcinoid

UR - https://www.scopus.com/pages/publications/0032809550

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DO - 10.1515/JPEM.1999.12.4.573

M3 - 文章

C2 - 10417976

AN - SCOPUS:0032809550

SN - 0334-018X

VL - 12

SP - 573

EP - 578

JO - Journal of Pediatric Endocrinology and Metabolism

JF - Journal of Pediatric Endocrinology and Metabolism

IS - 4

ER -

Ectopic ACTH syndrome due to thymic carcinoid tumor in a girl

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Keywords

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